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Predicting long-term outcome of Internet-delivered cognitive behavior therapy for social anxiety disorder using fMRI and support vector machine learning.

Translational psychiatry
Cognitive behavior therapy (CBT) is an effective treatment for social anxiety disorder (SAD), but many patients do not respond sufficiently and a substantial proportion relapse after treatment has ended. Predicting an individual's long-term clinical ...

BiNChE: a web tool and library for chemical enrichment analysis based on the ChEBI ontology.

BMC bioinformatics
BACKGROUND: Ontology-based enrichment analysis aids in the interpretation and understanding of large-scale biological data. Ontologies are hierarchies of biologically relevant groupings. Using ontology annotations, which link ontology classes to biol...

Transformation of standardized clinical models based on OWL technologies: from CEM to OpenEHR archetypes.

Journal of the American Medical Informatics Association : JAMIA
INTRODUCTION: The semantic interoperability of electronic healthcare records (EHRs) systems is a major challenge in the medical informatics area. International initiatives pursue the use of semantically interoperable clinical models, and ontologies h...

Identifying DNA-binding proteins by combining support vector machine and PSSM distance transformation.

BMC systems biology
BACKGROUND: DNA-binding proteins play a pivotal role in various intra- and extra-cellular activities ranging from DNA replication to gene expression control. Identification of DNA-binding proteins is one of the major challenges in the field of genome...

Aber-OWL: a framework for ontology-based data access in biology.

BMC bioinformatics
BACKGROUND: Many ontologies have been developed in biology and these ontologies increasingly contain large volumes of formalized knowledge commonly expressed in the Web Ontology Language (OWL). Computational access to the knowledge contained within t...

ENVIRONMENTS and EOL: identification of Environment Ontology terms in text and the annotation of the Encyclopedia of Life.

Bioinformatics (Oxford, England)
UNLABELLED: The association of organisms to their environments is a key issue in exploring biodiversity patterns. This knowledge has traditionally been scattered, but textual descriptions of taxa and their habitats are now being consolidated in centr...

Integrated semantics service platform for the Internet of Things: a case study of a smart office.

Sensors (Basel, Switzerland)
The Internet of Things (IoT) allows machines and devices in the world to connect with each other and generate a huge amount of data, which has a great potential to provide useful knowledge across service domains. Combining the context of IoT with sem...

A teleconference with three-dimensional surgical video presentation on the 'usual' Internet.

General thoracic and cardiovascular surgery
Endoscopic surgery employing three-dimensional (3D) video images, such as a robotic surgery, has recently become common. However, the number of opportunities to watch such actual 3D videos is still limited due to many technical difficulties associate...

Exploiting Semantic Web Technologies to Develop OWL-Based Clinical Practice Guideline Execution Engines.

IEEE journal of biomedical and health informatics
Computerizing paper-based CPG and then executing them can provide evidence-informed decision support to physicians at the point of care. Semantic web technologies especially web ontology language (OWL) ontologies have been profusely used to represent...

LinkRbrain: multi-scale data integrator of the brain.

Journal of neuroscience methods
BACKGROUND: LinkRbrain is an open-access web platform for multi-scale data integration and visualization of human brain data. This platform integrates anatomical, functional, and genetic knowledge produced by the scientific community.