AIMC Topic: Lymphoma, Extranodal NK-T-Cell

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Forecasting optimal treatments in relapsed/refractory mature T- and NK-cell lymphomas: A global PETAL Consortium study.

British journal of haematology
There is no standard of care in relapsed/refractory T-cell/natural killer-cell lymphomas. Patients often cycle through cytotoxic chemotherapy (CC), epigenetic modifiers (EM) or small molecule inhibitors (SMI) empirically. Ideal therapy at each line r...

Robust and interpretable deep learning system for prognostic stratification of extranodal natural killer/T-cell lymphoma.

European journal of nuclear medicine and molecular imaging
PURPOSE: Extranodal natural killer/T-cell lymphoma (ENKTCL) is an hematologic malignancy with prognostic heterogeneity. We aimed to develop and validate DeepENKTCL, an interpretable deep learning prediction system for prognosis risk stratification in...

Artificial intelligence for diagnosis and prognosis prediction of natural killer/T cell lymphoma using magnetic resonance imaging.

Cell reports. Medicine
Accurate diagnosis and prognosis prediction are conducive to early intervention and improvement of medical care for natural killer/T cell lymphoma (NKTCL). Artificial intelligence (AI)-based systems are developed based on nasopharynx magnetic resonan...

The identification of gene signatures in patients with extranodal NK/T-cell lymphoma from a pair of twins.

BMC cancer
BACKGROUND: There is no unified treatment standard for patients with extranodal NK/T-cell lymphoma (ENKTL). Cancer neoantigens are the result of somatic mutations and cancer-specific. Increased number of somatic mutations are associated with anti-can...

Weakly supervised deep learning for determining the prognostic value of F-FDG PET/CT in extranodal natural killer/T cell lymphoma, nasal type.

European journal of nuclear medicine and molecular imaging
PURPOSE: To develop a weakly supervised deep learning (WSDL) method that could utilize incomplete/missing survival data to predict the prognosis of extranodal natural killer/T cell lymphoma, nasal type (ENKTL) based on pretreatment F-FDG PET/CT resul...