AIMC Topic: Mammals

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Challenges in developing cell culture media using machine learning.

Biotechnology advances
Microbial and mammalian cells are widely used in the food, pharmaceutical, and medical industries. Developing or optimizing culture media is essential to improve cell culture performance as a critical technology in cell culture engineering. Methodolo...

Multi-task machine learning models for simultaneous prediction of tissue-to-blood partition coefficients of chemicals in mammals.

Environmental research
Tissue-to-blood partition coefficients (P) are crucial for assessing the distribution of chemicals in organisms. Given the lack of experimental data and laborious nature of experimental methods, there is an urgent need to develop efficient predictive...

How deep is the brain? The shallow brain hypothesis.

Nature reviews. Neuroscience
Deep learning and predictive coding architectures commonly assume that inference in neural networks is hierarchical. However, largely neglected in deep learning and predictive coding architectures is the neurobiological evidence that all hierarchical...

African bovid tribe classification using transfer learning and computer vision.

Annals of the New York Academy of Sciences
Objective analytical identification methods are still a minority in the praxis of paleobiological sciences. Subjective interpretation of fossils and their modifications remains a nonreplicable expert endeavor. Identification of African bovids is a cr...

A separable temporal convolutional networks based deep learning technique for discovering antiviral medicines.

Scientific reports
An alarming number of fatalities caused by the COVID-19 pandemic has forced the scientific community to accelerate the process of therapeutic drug discovery. In this regard, the collaboration between biomedical scientists and experts in artificial in...

Improving the classification of cardinality phenotypes using collections.

Journal of biomedical semantics
MOTIVATION: Phenotypes are observable characteristics of an organism and they can be highly variable. Information about phenotypes is collected in a clinical context to characterize disease, and is also collected in model organisms and stored in mode...

Species-specific wiring of cortical circuits for small-world networks in the primary visual cortex.

PLoS computational biology
Long-range horizontal connections (LRCs) are conspicuous anatomical structures in the primary visual cortex (V1) of mammals, yet their detailed functions in relation to visual processing are not fully understood. Here, we show that LRCs are key compo...

Rapid eye movement sleep loss associated cytomorphometric changes and neurodegeneration.

Sleep medicine
Rapid eye movement sleep (REMS) is essential for leading normal healthy living at least in higher-order mammals, including humans. In this review, we briefly survey the available literature for evidence linking cytomorphometric changes in the brain d...

Deep audio embeddings for vocalisation clustering.

PloS one
The study of non-human animals' communication systems generally relies on the transcription of vocal sequences using a finite set of discrete units. This set is referred to as a vocal repertoire, which is specific to a species or a sub-group of a spe...

GR-m6A: Prediction of N6-methyladenosine sites in mammals with molecular graph and residual network.

Computers in biology and medicine
RNA N6-methyladenine (m6A), which is produced by the methylation of the N6 position of eukaryotic adenine, is a relatively common post-transcriptional modification on the surface of the molecule, which frequently plays a crucial role in biological pr...