AIMC Topic: Meningitis, Cryptococcal

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Does infection alter antifungal distribution: an animal model exploring pharmacokinetic changes.

Future microbiology Apr 3, 2025
AIM: Assessing the disseminated meningitis caused by in Wistar rats and its impact on antifungal distribution by microdialysis (µD).
Brain Animals Male Rats, Wistar Rats Disease Models, Animal Antifungal Agents Fluconazole Cryptococcosis Meningitis, Cryptococcal Cryptococcus neoformans Microdialysis
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[Cerebral cryptococcosis and immune reconstitution inflammatory syndrome. Case report].

Revista medica de Chile Dec 1, 2018
We report a 45-year-old male with AIDS who had a Cryptococcus neoformans central nervous system infection. He was treated with amphotericin B deoxycholate subsequently changed to voriconazole due to systemic toxicity of the former. Plasma levels of v...
Humans Male Middle Aged Drug Combinations Antifungal Agents Voriconazole AIDS-Related Opportunistic Infections Amphotericin B Deoxycholic Acid Immune Reconstitution Inflammatory Syndrome Meningitis, Cryptococcal
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