World journal of microbiology & biotechnology
Nov 18, 2025
There is a growing concern about fungal infections and antifungal resistance among fungal species, underscoring the need for finding alternative treatments. Antifungal peptides (AFPs) are interesting and promising candidates for developing novel anti...
Fungi are closely associated with various diseases, among which Candida albicans (C. albicans) is recognized as an important pathogen in inflammatory bowel disease (IBD). Fungal pathogenicity is primarily mediated by virulence factors (VFs); therefor...
We conducted a multicenter retrospective analysis of 408 patients diagnosed with onychomycosis who attended three tertiary care Spanish hospitals. The study was conducted to assess the clinical characteristics and outcomes of onychomycosis patients u...
Fungi can cause devastating invasive infections, typically in immunocompromised patients. Treatment is complicated both by the evolutionary similarity between humans and fungi and by the frequent emergence of drug resistance. Studies in fungal pathog...
BACKGROUND: There is a pressing need to create innovative alternative treatment approaches considering the overuse of antifungal drugs causes the number of clinically isolated fluconazole-resistant species to increase. antimicrobial peptide (GmAMP)...
ETHNOPHARMACOLOGICAL RELEVANCE: For centuries, propolis has been one of the most important and popular antimicrobial (antibacterial and antifungal) agents used in traditional medicine worldwide, including Central and Eastern Europe. Despite centuries...
AIMS: C. albicans resistant strains have led to increasingly severe treatment challenges. Antimicrobial peptides with low resistance-inducing propensity for pathogens have been developed. A series of antimicrobial peptides de novo designed through ma...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Feb 8, 2025
Novel antifungal drugs that evade resistance are urgently needed for Candida infections. Antifungal peptides (AFPs) are potential candidates due to their specific mechanism of action, which makes them less prone to developing drug resistance. An AFP ...
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