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Mesencephalon

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Machine learning-assisted neurotoxicity prediction in human midbrain organoids.

Parkinsonism & related disorders
INTRODUCTION: Brain organoids are highly complex multi-cellular tissue proxies, which have recently risen as novel tools to study neurodegenerative diseases such as Parkinson's disease (PD). However, with increasing complexity of the system, usage of...

A Midbrain Inspired Recurrent Neural Network Model for Robust Change Detection.

The Journal of neuroscience : the official journal of the Society for Neuroscience
We present a biologically inspired recurrent neural network (RNN) that efficiently detects changes in natural images. The model features sparse, topographic connectivity (st-RNN), closely modeled on the circuit architecture of a "midbrain attention n...

PADS-Net: GAN-based radiomics using multi-task network of denoising and segmentation for ultrasonic diagnosis of Parkinson disease.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Parkinson disease (PD) is a prevalent neurodegenerative disorder, and its accurate diagnosis is crucial for timely intervention. We propose the PArkinson disease Denoising and Segmentation Network (PADS-Net), to simultaneously denoise and segment tra...