AIMC Topic: Mineralocorticoid Receptor Antagonists

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Individualized Treatment Effect Prediction with Machine Learning - Salient Considerations.

NEJM evidence Mar 26, 2024
BACKGROUND: Machine learning-based approaches that seek to accomplish individualized treatment effect prediction have gained traction; however, some salient challenges lack wider recognition.
Humans Machine Learning Algorithms Precision Medicine Female Aged Male Stroke Volume Middle Aged Treatment Outcome Heart Failure Spironolactone Mineralocorticoid Receptor Antagonists
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Treatment response to spironolactone in patients with heart failure with preserved ejection fraction: a machine learning-based analysis of two randomized controlled trials.

EBioMedicine Sep 7, 2023
BACKGROUND: Whether there is a subset of patients with heart failure with preserved ejection fraction (HFpEF) that benefit from spironolactone therapy is unclear. We applied a machine learning approach to identify responders and non-responders to spi...
Humans Machine Learning Algorithms Female Aged Male Stroke Volume Middle Aged Treatment Outcome Randomized Controlled Trials as Topic Heart Failure Spironolactone Mineralocorticoid Receptor Antagonists
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