AIMC Topic: NADPH Oxidases

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Curcumin Modulates NOX Gene Expression and ROS Production via P-Smad3C in TGF-β-Activated Hepatic Stellate Cells.

Iranian biomedical journal Oct 28, 2023
BACKGROUND: Liver fibrosis, associated with hepatic stellate cells (HSCs), occurs when a healthy liver sustains damage, thereby impairing its function. NADPH oxidases (NOXs), specifically isoforms 1, 2, and 4, play a role in reactive oxygen species (...
Humans RNA, Messenger Liver Cirrhosis Signal Transduction Reactive Oxygen Species Gene Expression Transforming Growth Factor beta Hepatic Stellate Cells Curcumin NADPH Oxidases
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Dysfunction of endothelial progenitor cells in hyperlipidemic rats involves the increase of NADPH oxidase derived reactive oxygen species production.

Canadian journal of physiology and pharmacology Oct 20, 2016
NADPH oxidase (NOX) is a major source of reactive oxygen species (ROS) in the body and it plays a key role in mediation of oxidative injury in the cardiovascular system. The purposes of this study are to evaluate the status of NOX in endothelial prog...
Phenotype Animals Male Rats Endothelial Progenitor Cells Rats, Sprague-Dawley Reactive Oxygen Species Lipoproteins, LDL NADPH Oxidases Hyperlipidemias Enzyme Inhibitors
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