AIMC Topic: Nanostructures

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A DNA robotic switch with regulated autonomous display of cytotoxic ligand nanopatterns.

Nature nanotechnology
The clustering of death receptors (DRs) at the membrane leads to apoptosis. With the goal of treating tumours, multivalent molecular tools that initiate this mechanism have been developed. However, DRs are also ubiquitously expressed in healthy tissu...

Bioinformatics and machine learning to support nanomaterial grouping.

Nanotoxicology
Nanomaterials (NMs) offer plenty of novel functionalities. Moreover, their physicochemical properties can be fine-tuned to meet the needs of specific applications, leading to virtually unlimited numbers of NM variants. Hence, efficient hazard and ris...

A Flexible Skin Bionic Thermally Comfortable Wearable for Machine Learning-Facilitated Ultrasensitive Sensing.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tremendous popularity is observed for multifunctional flexible electronics with appealing applications in intelligent electronic skins, human-machine interfaces, and healthcare sensing. However, the reported sensing electronics, mostly can hardly pro...

Ensuring food safety by artificial intelligence-enhanced nanosensor arrays.

Advances in food and nutrition research
Current analytical methods utilized for food safety inspection requires improvement in terms of their cost-efficiency, speed of detection, and ease of use. Sensor array technology has emerged as a food safety assessment method that applies multiple c...

Synergizing Nanomaterials and Artificial Intelligence in Advanced Optical Biosensors for Precision Antimicrobial Resistance Diagnosis.

ACS synthetic biology
Antimicrobial resistance (AMR) poses a critical global One Health concern, ensuing from unintentional and continuous exposure to antibiotics, as well as challenges in accurate contagion diagnostics. Addressing AMR requires a strategic approach that e...

AI-Powered Knowledge Base Enables Transparent Prediction of Nanozyme Multiple Catalytic Activity.

The journal of physical chemistry letters
Nanozymes are unique materials with many valuable properties for applications in biomedicine, biosensing, environmental monitoring, and beyond. In this work, we developed a machine learning (ML) approach to search for new nanozymes and deployed a web...

Engineering mannose-functionalized nanostructured lipid carriers by sequential design using hybrid artificial intelligence tools.

Drug delivery and translational research
Nanostructured lipid carriers (NLCs) hold significant promise as drug delivery systems (DDS) owing to their small size and efficient drug-loading capabilities. Surface functionalization of NLCs can facilitate interaction with specific cell receptors,...

Machine learning in nanozymes: from design to application.

Biomaterials science
Nanozymes, a distinctive class of nanomaterials endowed with enzyme-like activity and kinetics akin to enzyme-catalysed reactions, present several advantages over natural enzymes, including cost-effectiveness, heightened stability, and adjustable act...

Persistent Luminescence Lifetime-Based Near-Infrared Nanoplatform via Deep Learning for High-Fidelity Biosensing of Hypochlorite.

Analytical chemistry
In light of deep tissue penetration and ultralow background, near-infrared (NIR) persistent luminescence (PersL) bioprobes have become powerful tools for bioapplications. However, the inhomogeneous signal attenuation may significantly limit its appli...

Biomolecular Adsorption on Nanomaterials: Combining Molecular Simulations with Machine Learning.

Journal of chemical information and modeling
Adsorption free energies of 32 small biomolecules (amino acids side chains, fragments of lipids, and sugar molecules) on 33 different nanomaterials, computed by the molecular dynamics - metadynamics methodology, have been analyzed using statistical m...