AIMC Topic: Hydrogels
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Recent progress in multifunctional theranostic hydrogels: the cornerstone of next-generation wound care technologies.
Biomaterials science
Aug 5, 2025
Theranostic hydrogels represent a groundbreaking approach by integrating therapeutic and diagnostic capabilities within a single platform, enabling real-time monitoring of wounds and precise treatment applications. These advanced materials are engine...
Liposome-encapsulated AICAR hydrogel regulates macrophage metabolic reprogramming via SIK1 activation to alleviate osteoarthritis.
Journal of nanobiotechnology
Jul 5, 2025
BACKGROUND: Osteoarthritis (OA), the most prevalent joint disorder, is characterized by a complex etiology and a lack of safe and effective therapeutic interventions. Emerging evidence suggests that immune cell dysregulation plays a pivotal role in t...
Self-assembling peptide hydrogels: design, mechanisms, characterization, and biomedical applications.
Soft matter
Jun 19, 2025
Self-assembled peptide hydrogels have emerged as a research frontier in biomedical engineering due to their exceptional water-retention capacity and spatiotemporal drug release kinetics. Researchers can fabricate biomaterials with customizable struct...
Magnetic-Driven Hydrogel Robots Loaded with Mitomycin for Active Therapy of Bladder Cancer.
ACS applied materials & interfaces
Jun 16, 2025
Intravesical drug instillation is a common treatment for bladder cancer, but it suffers from poor targeting and suboptimal patient experience due to the influence of gravity. Here, we innovatively designed a bladder cancer treatment method using sodi...
Multimodal information structuring with single-layer soft skins and high-density electrical impedance tomography.
Science robotics
Jun 11, 2025
The human skin can reliably capture a wide range of multimodal data over a large surface while providing a soft interface. Artificial technologies using microelectromechanical systems (MEMS) can emulate these biological functions but present numerous...
In situ foliar augmentation of multiple species for optical phenotyping and bioengineering using soft robotics.
Science robotics
Jun 11, 2025
Precision agriculture aims to increase crop yield while reducing the use of harmful chemicals, such as pesticides and excess fertilizer, using minimal, tailored interventions. However, these strategies are limited by factors such as sensor quality, w...
Tyramide signal amplification for a highly sensitive multiplex immunoassay based on encoded hydrogel microparticles.
The Analyst
May 12, 2025
Proteins play a crucial role as mediators of immune regulation, homeostasis, and metabolism, making their quantification essential for understanding disease mechanisms in biomedical research and clinical diagnostics. However, conventional methods whe...
Light-microscopy-based connectomic reconstruction of mammalian brain tissue.
Nature
May 7, 2025
The information-processing capability of the brain's cellular network depends on the physical wiring pattern between neurons and their molecular and functional characteristics. Mapping neurons and resolving their individual synaptic connections can b...
Machine learning-assisted strategies to enhance the mechanical properties of PVA hydrogels.
Journal of the mechanical behavior of biomedical materials
Apr 19, 2025
Polyvinyl alcohol (PVA) hydrogels have garnered increasing interest in the field of biomedical materials due to their excellent biocompatibility and controllable mechanical properties. Although various preparation strategies such as freeze-thaw cycle...
Biofabrication of HepG2 Cells-Laden 3D Structures Using Nanocellulose-Reinforced Gelatin-Based Hydrogel Bioinks: Materials Characterization, Cell Viability Assessment, and Metabolomic Analysis.
ACS biomaterials science & engineering
Apr 16, 2025
The successful replication of the intricate architecture of human tissues remains a major challenge in the biomedical area. Three-dimensional (3D) bioprinting has emerged as a promising approach for the biofabrication of living tissue analogues, taki...
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