AIMC Topic: Natural Language Processing

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EvidenceOutcomes: A Dataset of Clinical Trial Publications with Clinically Meaningful Outcomes.

Studies in health technology and informatics
The fundamental process of evidence extraction in evidence-based medicine relies on identifying PICO elements, with Outcomes being the most complex and often overlooked. To address this, we introduce EvidenceOutcomes, a large annotated corpus of clin...

PheCatcher: Leveraging LLM-Generated Synthetic Data for Automated Phenotype Definition Extraction from Biomedical Literature.

Studies in health technology and informatics
Phenotype definitions are crucial for the progression of precision and personalized medicine. Although phenotype knowledge bases such as PheKB and the OHDSI library are available, they rely heavily on manual input. This study introduces PheCatcher, a...

A Framework for Extracting, and Validating Named-Entities to Integrate Openehr Using the Example of Free Text Molecular Genetic Findings.

Studies in health technology and informatics
Processing and extracting information from unstructured texts written by physicians in Hospitals is still an open problem. There is no efficient solution that ensures the reliability of the extracted information without any human intervention. Many f...

Natural Language Processing-Based Approach to Detect Common Adverse Events of Anticancer Agents from Unstructured Clinical Notes: A Time-to-Event Analysis.

Studies in health technology and informatics
This study assessed the effectiveness of natural language processing (NLP) in detecting adverse events (AEs) from anticancer agents by analyzing data from over 39,000 cancer patients. A specialized machine learning model identified known AEs from ant...

Empirical Antonym Implementation in the UMLS SPECIALIST Lexicon.

Studies in health technology and informatics
Antonyms are words that have opposite or contrasting meanings in a specific domain. For example, "increase" is the opposite of "decrease" in the domain of "quantity". Antonyms play an important role in NLP applications to improve performance. This pa...

Clinical Trial Eligibility Criteria Decomposition and Parsing with Large Language Models.

Studies in health technology and informatics
Clinical trial eligibility criteria, often presented as complex free text, pose significant challenges for automated processing. This study introduces a Decomposition and Parsing (DP) workflow to address these challenges by systematically breaking do...

Can Generative LLMs Help Classify Imbalanced Real-World Data? Exploring Rare Diseases on Social Media.

Studies in health technology and informatics
Developmental and Epileptic Encephalopathies (DEEs) are rare, severe conditions often discussed by families on social media, offering valuable insights into their experiences. Identifying these messages amidst unrelated content is crucial but challen...

Performance of Open-Source Large Language Models to Extract Symptoms from Clinical Notes.

Studies in health technology and informatics
In this study, we examined how well the open-source foundational large language models (LLMs) can extract symptoms and signs (S&S), along with their corresponding ICD-10 codes, from clinical notes found in the public MTSamples dataset. The dataset co...

Human in the Loop: Embedding Medical Expert Input in Large Language Models for Clinical Applications.

Studies in health technology and informatics
The state-of-the-art performance of large language models (LLMs) in medical natural language (NLP) tasks, including medical query answering, summarization of clinical notes, and generation of medical reports has led to the development of a large numb...

An Ensemble Approach Integrating Retrieval-Augmented Large Language Models and Boosting Algorithms for Enhanced Catatonia Phenotyping.

Studies in health technology and informatics
A critical first step in using large-scale data to study catatonia is the development of precise phenotyping algorithms that can identify instances of the condition. In this work, we present an ensemble approach that combines retrieval-augmented gene...