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Natural Language Processing

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Harnessing explainable artificial intelligence for patient-to-clinical-trial matching: A proof-of-concept pilot study using phase I oncology trials.

PloS one
This study aims to develop explainable AI methods for matching patients with phase 1 oncology clinical trials using Natural Language Processing (NLP) techniques to address challenges in patient recruitment for improved efficiency in drug development....

Automated Identification of Heart Failure With Reduced Ejection Fraction Using Deep Learning-Based Natural Language Processing.

JACC. Heart failure
BACKGROUND: The lack of automated tools for measuring care quality limits the implementation of a national program to assess guideline-directed care in heart failure with reduced ejection fraction (HFrEF).

Accuracy of natural language processors for patients seeking inguinal hernia information.

Surgical endoscopy
BACKGROUND: NLPs such as ChatGPT are novel sources of online healthcare information that are readily accessible and integrated into internet search tools. The accuracy of NLP-generated responses to health information questions is unknown.

From pre-training to fine-tuning: An in-depth analysis of Large Language Models in the biomedical domain.

Artificial intelligence in medicine
In this study, we delve into the adaptation and effectiveness of Transformer-based, pre-trained Large Language Models (LLMs) within the biomedical domain, a field that poses unique challenges due to its complexity and the specialized nature of its da...

Enhancing Arabidopsis thaliana ubiquitination site prediction through knowledge distillation and natural language processing.

Methods (San Diego, Calif.)
Protein ubiquitination is a critical post-translational modification (PTM) involved in diverse biological processes and plays a pivotal role in regulating physiological mechanisms and disease states. Despite various efforts to develop ubiquitination ...

ChatGPT-4 extraction of heart failure symptoms and signs from electronic health records.

Progress in cardiovascular diseases
BACKGROUND: Natural language processing (NLP) can facilitate research utilizing data from electronic health records (EHRs). Large language models can potentially improve NLP applications leveraging EHR notes. The objective of this study was to assess...

Distributional hypothesis as isomorphism between word-word co-occurrence and analogical parallelograms.

PloS one
Most of the modern natural language processing (NLP) techniques are based on the vector space models of language, in which each word is represented by a vector in a high dimensional space. One of the earliest successes was demonstrated by the four-te...

PLRTE: Progressive learning for biomedical relation triplet extraction using large language models.

Journal of biomedical informatics
Document-level relation triplet extraction is crucial in biomedical text mining, aiding in drug discovery and the construction of biomedical knowledge graphs. Current language models face challenges in generalizing to unseen datasets and relation typ...

Semiology Extraction and Machine Learning-Based Classification of Electronic Health Records for Patients With Epilepsy: Retrospective Analysis.

JMIR medical informatics
BACKGROUND: Obtaining and describing semiology efficiently and classifying seizure types correctly are crucial for the diagnosis and treatment of epilepsy. Nevertheless, there exists an inadequacy in related informatics resources and decision support...

Enhancing Aortic Aneurysm Surveillance: Transformer Natural Language Processing for Flagging and Measuring in Radiology Reports.

Annals of vascular surgery
BACKGROUND: Incidental findings of aortic aneurysms (AAs) often go unreported, and established patients are frequently lost to follow-up. Natural language processing (NLP) offers a promising solution to address these issues. While rule-based NLP meth...