AIMC Topic: Neuraminidase

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Machine Learning Using Template-Based-Predicted Structure of Haemagglutinin Predicts Pathogenicity of Avian Influenza.

Journal of microbiology and biotechnology Aug 6, 2024
Deep learning presents a promising approach to complex biological classifications, contingent upon the availability of well-curated datasets. This study addresses the challenge of analyzing three-dimensional protein structures by introducing a novel ...
Influenza A virus Deep Learning Computational Biology Influenza in Birds Birds Genome, Viral Hemagglutinin Glycoproteins, Influenza Virus Hemagglutinins Principal Component Analysis Neuraminidase Neural Networks, Computer Algorithms Animals Machine Learning
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Drug Design of Targeted Chemical Libraries Based on Artificial Intelligence and Pair-Based Multiobjective Optimization.

Journal of chemical information and modeling Sep 9, 2020
Artificial intelligence and multiobjective optimization represent promising solutions to bridge chemical and biological landscapes by addressing the automated design of compounds as a result of a humanlike creative process. In the present study, we ...
Drug Design Influenza A virus Antiviral Agents SARS-CoV-2 Molecular Docking Simulation Acetylcholinesterase Cholinesterase Inhibitors Enzyme Inhibitors Coronavirus Infections Neuraminidase Humans Neural Networks, Computer Pandemics COVID-19 Artificial Intelligence Coronavirus 3C Proteases Viral Nonstructural Proteins Cysteine Endopeptidases Betacoronavirus Small Molecule Libraries Pneumonia, Viral
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Conservation region finding for influenza A viruses by machine learning methods of N-linked glycosylation sites and B-cell epitopes.

Mathematical biosciences Jun 17, 2019
Influenza type A, a serious infectious disease of the human respiratory tract, poses an enormous threat to human health worldwide. It leads to high mortality rates in poultry, pigs, and humans. The primary target identity regions for the human immune...
Conserved Sequence Epitopes, B-Lymphocyte Hemagglutinin Glycoproteins, Influenza Virus Neuraminidase Viral Proteins Machine Learning Influenza A virus Humans Databases, Protein Glycosylation Influenza, Human
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Using Support Vector Machine (SVM) for Classification of Selectivity of H1N1 Neuraminidase Inhibitors.

Molecular informatics Jan 15, 2016
Inhibition of the neuraminidase is one of the most promising strategies for preventing influenza virus spreading. 479 neuraminidase inhibitors are collected for dataset 1 and 208 neuraminidase inhibitors for A/P/8/34 are collected for dataset 2. Usin...
Antiviral Agents Support Vector Machine Computer Simulation Neuraminidase Influenza A Virus, H1N1 Subtype Enzyme Inhibitors Quantitative Structure-Activity Relationship
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Discovery of Influenza A virus neuraminidase inhibitors using support vector machine and Naïve Bayesian models.

Molecular diversity Dec 21, 2015
Neuraminidase (NA) is a critical enzyme in the life cycle of influenza virus, which is known as a successful paradigm in the design of anti-influenza agents. However, to date there are no classification models for the virtual screening of NA inhibito...
Influenza A Virus, H1N1 Subtype Influenza A Virus, H3N2 Subtype Bayes Theorem Neuraminidase Enzyme Inhibitors Computational Biology Support Vector Machine Drug Discovery
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Citations alone were enough to predict favorable conclusions in reviews of neuraminidase inhibitors.

Journal of clinical epidemiology Oct 22, 2014
OBJECTIVES: To examine the use of supervised machine learning to identify biases in evidence selection and determine if citation information can predict favorable conclusions in reviews about neuraminidase inhibitors.
Research Design Neuraminidase Humans Influenza, Human Enzyme Inhibitors Review Literature as Topic Artificial Intelligence Selection Bias Publications
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A novel reassortant avian influenza H4N6 virus isolated from an environmental sample during a surveillance in Maharashtra, India.

The Indian journal of medical research Jun 1, 2021
BACKGROUND & OBJECTIVES: Low pathogenic avian influenza (LPAI) viruses cause mild clinical illness in domestic birds. Migratory birds are a known reservoir for all subtypes of avian influenza (AI) viruses. The objective of the study was to characteri...
Animals, Wild Humans Phylogeny Influenza in Birds Influenza A virus Animals Birds India Neuraminidase
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