AIMC Topic: Oxazines

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Durability of dolutegravir plus boosted darunavir as salvage or simplification of salvage regimens in HIV-1 infected, highly treatment-experienced subjects.

HIV clinical trials Dec 1, 2018
BACKGROUND: Dolutegravir (DTG) plus boosted darunavir (bDRV) is a compact, adherence-friendly salvage regimen with the highest genetic barrier to HIV-1 resistance.
Humans Female Reproducibility of Results Aged Adult Male Middle Aged HIV Infections Cohort Studies Pyridones Oxazines Heterocyclic Compounds, 3-Ring Piperazines Italy HIV-1 Darunavir HIV Protease Inhibitors HIV Integrase Inhibitors Salvage Therapy
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Microwave-assisted One-pot Efficient Synthesis of Functionalized 2-Oxo-2-phenylethylidenes-linked 2-Oxobenzo[1,4]oxazines and 2-Oxoquino[1,4]oxalines: Synthetic Applications, Antioxidant Activity, SAR and Cytotoxic Studies.

Acta chimica Slovenica Dec 1, 2017
A microwave-assisted, environmentally benign green protocol for the synthesis of functionalized (Z)-3-(2-oxo-2-phenylethylidene)-3, 4-dihydro-2H-benzo[b][1,4]oxazin-2-ones (11a-n) in excellent yields (upto 97%) and (Z)-3-(2-oxo-2-phenylethylidene)-3,...
Animals Antineoplastic Agents Mice Antioxidants Structure-Activity Relationship Oxazines 3T3 Cells Microwaves Quinoxalines
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