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Protein Corona

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Investigation of the influence of protein corona composition on gold nanoparticle bioactivity using machine learning approaches.

SAR and QSAR in environmental research
The understanding of the mechanisms and interactions that occur when nanomaterials enter biological systems is important to improve their future use. The adsorption of proteins from biological fluids in a physiological environment to form a corona on...

Engineered nanoparticles enable deep proteomics studies at scale by leveraging tunable nano-bio interactions.

Proceedings of the National Academy of Sciences of the United States of America
SignificanceDeep profiling of the plasma proteome at scale has been a challenge for traditional approaches. We achieve superior performance across the dimensions of precision, depth, and throughput using a panel of surface-functionalized superparamag...