AIMC Topic: Protein Corona

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Corona Dynamics of Nanoparticles and Their Functional Design Space in Molecular Sensing.

ACS nano
As nanomaterials increasingly interact with complex biological environments, understanding and designing their interfacial layers is critical for enabling functional and responsive behaviors. The protein corona, a spontaneously formed biomolecular la...

Debugging the dynamics of protein corona: Formation, composition, challenges, and applications at the nano-bio interface.

Advances in colloid and interface science
The intricate interplay between nanomaterials and the biological molecules has garnered considerable interest in understanding the dynamics of protein corona formation at the nano-bio interface. This review provides an in-depth exploration of protein...

Engineered nanoparticles enable deep proteomics studies at scale by leveraging tunable nano-bio interactions.

Proceedings of the National Academy of Sciences of the United States of America
SignificanceDeep profiling of the plasma proteome at scale has been a challenge for traditional approaches. We achieve superior performance across the dimensions of precision, depth, and throughput using a panel of surface-functionalized superparamag...

Investigation of the influence of protein corona composition on gold nanoparticle bioactivity using machine learning approaches.

SAR and QSAR in environmental research
The understanding of the mechanisms and interactions that occur when nanomaterials enter biological systems is important to improve their future use. The adsorption of proteins from biological fluids in a physiological environment to form a corona on...