MOTIVATION: Experimental testing and manual curation are the most precise ways for assigning Gene Ontology (GO) terms describing protein functions. However, they are expensive, time-consuming and cannot cope with the exponential growth of data genera...
Mathematical biosciences and engineering : MBE
Sep 20, 2022
In this paper, the distributed state estimation problem of genetic regulatory networks (GRNs) with hidden Markovian jumping parameters (HMJPs) is explored. Furthermore, in order to improve the communication efficiency among state estimation sensors, ...
Noncoding RNAs (ncRNAs) have recently attracted considerable attention due to their key roles in biology. The ncRNA-proteins interaction (NPI) is often explored to reveal some biological activities that ncRNA may affect, such as biological traits, di...
The X-ray diffraction (XRD) technique based on crystallography is the main experimental method to analyze the three-dimensional structure of proteins. The production process of protein crystals on which the XRD technique relies has undergone multiple...
Protein S-sulfinylation is an important posttranslational modification that regulates a variety of cell and protein functions. This modification has been linked to signal transduction, redox homeostasis and neuronal transmission in studies. Therefore...
A newly invented post-translational modification (PTM), phosphoglycerylation, has shown its essential role in the construction and functional properties of proteins and dangerous human diseases. Hence, it is very urgent to know about the molecular me...
MOTIVATION: Characterization of protein subcellular localization has become an important and long-standing task in bioinformatics and computational biology, which provides valuable information for elucidating various cellular functions of proteins an...
MOTIVATION: Computational methods for the prediction of protein-protein interactions (PPIs), while important tools for researchers, are plagued by challenges in generalizing to unseen proteins. Datasets used for modelling protein-protein predictions ...
MOTIVATION: Recently, AlphaFold2 achieved high experimental accuracy for the majority of proteins in Critical Assessment of Structure Prediction (CASP 14). This raises the hope that one day, we may achieve the same feat for RNA structure prediction f...
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