The biomedical literature contains a sufficient number of chemical-protein interactions (CPIs). Automatic extraction of CPI is a crucial task in the biomedical domain, which has excellent benefits for precision medicine, drug discovery and basic biom...
Recently joint modeling methods of entity and relation exhibit more promising results than traditional pipelined methods in general domain. However, they are inappropriate for the biomedical domain due to numerous overlapping relations in biomedical ...
PURPOSE: The objective of this study was to assess the classification capability of Breast Imaging Reporting and Data System (BI-RADS) ultrasound feature descriptors targeting established commercial transcriptomic gene signatures that guide managemen...
Computer methods and programs in biomedicine
Jan 9, 2020
BACKGROUND AND OBJECTIVE: The interrupted time-series (ITS) concept is performed using linear regression to evaluate the impact of policy changes in public health at a specific time. Objectives of this study were to verify, with an artificial intelli...
The Journal of allergy and clinical immunology
Dec 26, 2019
The wide adoption of electronic health record systems in health care generates big real-world data that open new venues to conduct clinical research. As a large amount of valuable clinical information is locked in clinical narratives, natural languag...
Extracting biological relations from biomedical literature can deliver personalized treatment to individual patients based on their genomic profiles. In this paper, we present a novel sentence-level attention-based deep neural network to predict the ...
Proceedings of the National Academy of Sciences of the United States of America
Dec 23, 2019
Background fluorescence, especially when it exhibits undesired spatial features, is a primary factor for reduced image quality in optical microscopy. Structured background is particularly detrimental when analyzing single-molecule images for 3-dimens...
BMC medical informatics and decision making
Dec 23, 2019
BACKGROUND: The medical community uses a variety of data standards for both clinical and research reporting needs. ISO 11179 Common Data Elements (CDEs) represent one such standard that provides robust data point definitions. Another standard is the ...
The field of precision medicine aims to tailor treatment based on patient-specific factors in a reproducible way. To this end, estimating an optimal individualized treatment regime (ITR) that recommends treatment decisions based on patient characteri...