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Rotavirus

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Isolation and Pathogenicity Analysis of a G5P[23] Porcine Rotavirus Strain.

Viruses
(1) Background: Group A rotaviruses (RVAs) are the primary cause of severe intestinal diseases in piglets. Porcine rotaviruses (PoRVs) are widely prevalent in Chinese farms, resulting in significant economic losses to the livestock industry. However,...

Postbiotic Activities of : Impacts on Viability, Structural Integrity, and Cell Death Markers in Human Intestinal C2BBe1 Cells.

Pathogens (Basel, Switzerland)
Acute diarrheal disease (ADD) caused by rotavirus (RV) contributes significantly to morbidity and mortality in children under five years of age. Currently, there are no specific drugs for the treatment of RV infections. Previously, we reported the an...

A retrospective study using machine learning to develop predictive model to identify rotavirus-associated acute gastroenteritis in children.

PeerJ
BACKGROUND: Rotavirus is the leading cause of severe dehydrating diarrhea in children under 5 years worldwide. Timely diagnosis is critical, but access to confirmatory testing is limited in hospital settings. Machine learning (ML) models have shown p...

Analysis of protein determinants of genotype-specific properties of group a rotaviruses using machine learning.

Computers in biology and medicine
Group A rotaviruses (RVAs) are the leading cause of viral diarrhoea across various host species, including mammals and birds. The VP7 and VP4 proteins of these viruses play critical roles in determining genotype specificity, influencing viral infecti...