AIMC Topic: Tight Junctions

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Role of tight junctions in three-dimensional mechanical model of blood-brain barrier.

Journal of biomechanics Jun 7, 2025
The increasing prevalence of central nervous system (CNS) disorders has imposed a significant social and economic burden on healthcare systems. The blood-brain barrier (BBB) presents a major challenge for effective drug delivery to the brain, hinderi...
Humans Computer Simulation Blood-Brain Barrier Biomechanical Phenomena Animals Models, Biological Tight Junctions Stress, Mechanical Endothelial Cells Finite Element Analysis
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Postbiotic Activities of : Impacts on Viability, Structural Integrity, and Cell Death Markers in Human Intestinal C2BBe1 Cells.

Pathogens (Basel, Switzerland) Dec 23, 2023
Acute diarrheal disease (ADD) caused by rotavirus (RV) contributes significantly to morbidity and mortality in children under five years of age. Currently, there are no specific drugs for the treatment of RV infections. Previously, we reported the an...
Humans Intestines Apoptosis Cell Line Cell Survival Probiotics Bacterial Proteins Rotavirus Rotavirus Infections Bifidobacterium adolescentis Cell Death Tight Junctions
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Machine-Learning-Based Approach to Decode the Influence of Nanomaterial Properties on Their Interaction with Cells.

ACS applied materials & interfaces Dec 29, 2020
In an nanotoxicity system, cell-nanoparticle (NP) interaction leads to the surface adsorption, uptake, and changes into nuclei/cell phenotype and chemistry, as an indicator of oxidative stress, genotoxicity, and carcinogenicity. Different types of n...
Machine Learning Animals Cell Proliferation Carbon Epithelial Cells Zonula Occludens-1 Protein Gold Metal Nanoparticles Dogs Madin Darby Canine Kidney Cells Tight Junctions Dendrimers Cell Nucleus Actin Cytoskeleton Cell Nucleus Shape
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