AIMC Topic: Serotonin and Noradrenaline Reuptake Inhibitors

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Machine Learning Tool for New Selective Serotonin and Serotonin-Norepinephrine Reuptake Inhibitors.

Molecules (Basel, Switzerland) Jan 31, 2025
Depression, a serious mood disorder, affects about 5% of the population. Currently, there are two groups of antidepressants that are the first-line treatment for depressive disorder: selective serotonin reuptake inhibitors and serotonin-norepinephrin...
Humans Machine Learning Quantitative Structure-Activity Relationship Antidepressive Agents Norepinephrine Plasma Membrane Transport Proteins Serotonin Plasma Membrane Transport Proteins Serotonin and Noradrenaline Reuptake Inhibitors Selective Serotonin Reuptake Inhibitors
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GWAS-based machine learning approach to predict duloxetine response in major depressive disorder.

Journal of psychiatric research Feb 2, 2018
Major depressive disorder (MDD) is one of the most prevalent psychiatric disorders and is commonly treated with antidepressant drugs. However, large variability is observed in terms of response to antidepressants. Machine learning (ML) models may be ...
Humans Prognosis Female Adult Sensitivity and Specificity Male Middle Aged Depressive Disorder, Major Genome-Wide Association Study Polymorphism, Single Nucleotide Support Vector Machine Outcome Assessment, Health Care Duloxetine Hydrochloride Serotonin and Noradrenaline Reuptake Inhibitors
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