Bioinformatics (Oxford, England)
Jan 1, 2023
MOTIVATION: As more data of experimentally determined protein structures are becoming available, data-driven models to describe protein sequence-structure relationships become more feasible. Within this space, the amino acid sequence design of protei...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2023
Novel design of proteins to target receptors for treatment or tissue augmentation has come to the fore owing to advancements in computing power, modeling frameworks, and translational successes. Shorter proteins, or peptides, can offer combinatorial ...
Bioinformatics (Oxford, England)
Jan 1, 2023
MOTIVATION: While multi-channel fluorescence microscopy is a vital imaging method in biological studies, the number of channels that can be imaged simultaneously is limited by technical and hardware limitations such as emission spectra cross-talk. On...
Bioinformatics (Oxford, England)
Jan 1, 2023
SUMMARY: The development of new vaccines and antibody therapeutics typically takes several years and requires over $1bn in investment. Accurate knowledge of the paratope (antibody binding site) can speed up and reduce the cost of this process by impr...
Technology and health care : official journal of the European Society for Engineering and Medicine
Jan 1, 2023
BACKGROUND: The digital twin concept is the virtual model based on entity design measures, which is used in many enterprises' virtual workshop design models for workshop production scheduling and optimization. However, in the field of medical rehabil...
Bioinformatics (Oxford, England)
Dec 13, 2022
SUMMARY: In recent years, Deep Learning (DL) has been increasingly used in many fields, in particular in image recognition, due to its ability to solve problems where traditional machine learning algorithms fail. However, building an appropriate DL m...
The Journal of the Acoustical Society of America
Dec 1, 2022
This work presents an open-source matlab software package for exploiting recent advances in extracting tonal signals from large acoustic data sets. A whistle extraction algorithm published by Li, Liu, Palmer, Fleishman, Gillespie, Nosal, Shiu, Klinck...
Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
Dec 1, 2022
Evidence-based medicine, outcomes management, and multidisciplinary systems are laying the foundation for radiology on the cusp of a new day. Environmental and operational forces coupled with technological advancements are redefining the veterinary r...
Bioinformatics (Oxford, England)
Nov 30, 2022
MOTIVATION: Hypothesis generation (HG) refers to the discovery of meaningful implicit connections between disjoint scientific terms, which is of great significance for drug discovery, prediction of drug side effects and precision treatment. More rece...
European review for medical and pharmacological sciences
Nov 1, 2022
Many technological advances have entered the clinical routine of Computed Tomography (CT) imaging. The new CT scanners have specific solutions in gantry design to bear the mechanical solicitations. The X-ray tubes have been improved for faster acquis...