In this study, we built classification models using machine learning techniques to predict the bioactivity of non-covalent inhibitors of Bruton's tyrosine kinase (BTK) and to provide interpretable and transparent explanations for these predictions. T...
Modern wastewater treatment plants base their biological processes on advanced control systems which ensure compliance with discharge limits and minimize energy consumption responding to information from on-line probes. The correct readings of probes...
Prevention is more important than treatment, and the incidence of intracerebral hemorrhage can be effectively reduced by intervening on the risk factors of intracerebral hemorrhage. By studying the risk factors of spontaneous intracerebral hemorrhage...
Neural networks : the official journal of the International Neural Network Society
Jul 17, 2023
Support vector machines (SVMs) are powerful statistical learning tools, but their application to large datasets can cause time-consuming training complexity. To address this issue, various instance selection (IS) approaches have been proposed, which ...
Neural networks : the official journal of the International Neural Network Society
Jul 17, 2023
Multi-view learning aims to make use of the advantages of different views to complement each other and fully mines the potential information in the data. However, the complexity of multi-view learning algorithm is much higher than that of single view...
Computer methods and programs in biomedicine
Jul 16, 2023
CONTEXT: Continuous blood pressure (BP) monitoring plays an important role while treating various cardiovascular diseases and hypertension. A high correlation between arterial blood pressure (ABP) and Photoplethysmogram (PPG) signal enables using a P...
Environmental monitoring and assessment
Jul 5, 2023
Aquaculture fish diseases pose a serious threat to the security of food supplies. Fish species vary widely, and because they resemble one another so much, it is challenging to distinguish between them based solely on appearance. To stop the spread of...
Obstructive sleep apnea (OSA) has a heavy health-related burden on patients and the healthcare system. Continuous positive airway pressure (CPAP) is effective in treating OSA, but adherence to it is often inadequate. A promising solution is to detect...
International journal of biological macromolecules
Jul 4, 2023
The identification of antioxidant proteins is a challenging yet meaningful task, as they can protect against the damage caused by some free radicals. In addition to time-consuming, laborious, and expensive experimental identification methods, efficie...
Journal of computer-aided molecular design
Jun 29, 2023
Drug candidates identified by the pharmaceutical industry typically have unique structural characteristics to ensure they interact strongly and specifically with their biological targets. Identifying these characteristics is a key challenge for devel...
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