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Synthetic Biology

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Synthetic data in machine learning for medicine and healthcare.

Nature biomedical engineering
The proliferation of synthetic data in artificial intelligence for medicine and healthcare raises concerns about the vulnerabilities of the software and the challenges of current policy.

A cellular platform for the development of synthetic living machines.

Science robotics
Robot swarms have, to date, been constructed from artificial materials. Motile biological constructs have been created from muscle cells grown on precisely shaped scaffolds. However, the exploitation of emergent self-organization and functional plast...

[Preface for special issue on industrial microorganisms: innovation and breakthrough (2021)].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology
Industrial microorganisms and their products are widely used in various fields such as industry, agriculture, and medicine, which play a pivotal role in economy. Efficient industrial strains are the key to improve production efficiency, and advanced ...

Sequence-to-function deep learning frameworks for engineered riboregulators.

Nature communications
While synthetic biology has revolutionized our approaches to medicine, agriculture, and energy, the design of completely novel biological circuit components beyond naturally-derived templates remains challenging due to poorly understood design rules....

A deep learning approach to programmable RNA switches.

Nature communications
Engineered RNA elements are programmable tools capable of detecting small molecules, proteins, and nucleic acids. Predicting the behavior of these synthetic biology components remains a challenge, a situation that could be addressed through enhanced ...

Sequencing enabling design and learning in synthetic biology.

Current opinion in chemical biology
The ability to read and quantify nucleic acids such as DNA and RNA using sequencing technologies has revolutionized our understanding of life. With the emergence of synthetic biology, these tools are now being put to work in new ways - enabling de no...

A machine learning Automated Recommendation Tool for synthetic biology.

Nature communications
Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules such as renewable biofuels or anticancer drugs. However, traditional synthetic biology approaches involve ad-hoc engineering practices, which lead to long develop...