AIMC Topic: Tigecycline

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Construction and temporal external validation of interpretable machine-learning models for predicting tigecycline-associated hypofibrinogenemia.

European journal of clinical pharmacology
BACKGROUND AND PURPOSE: There is a paucity of available clinical tools with which to accurately predict the risk of tigecycline-associated hypofibrinogenemia, an adverse reaction with a high incidence and serious consequences. This study aimed to dev...

Molecular mechanisms of antibiotic co-resistance among carbapenem resistant Acinetobacter baumannii.

Journal of infection in developing countries
INTRODUCTION: The spread of carbapenem-resistant Acinetobacter baumannii (CRAB) is difficult to control especially in the hospitals due to the successful mobilization and evolution of the genetic elements harboring the resistant determinants. The stu...