BACKGROUND: Oxford Nanopore Technologies (Oxford Nanopore Technologies (ONT)) sequencing enables direct, long-read sequencing of DNA and RNA, preserving nucleotide modifications. During basecalling, deep neural networks translate raw nanopore signals... read more
BACKGROUND: The deployment of machine learning in clinical settings is often hindered by the limited generalizability of the models. Models that perform well during development tend to underperform in new environments, limiting their clinical utility... read more
OBJECTIVE: Epilepsy surgery in people with focal cortical dysplasia (FCD) requires accurate removal of all epileptogenic tissue, and outcome is difficult to predict. We explored whether spectral entropy, a fast computable electroencephalographic (EEG... read more
AIMS: Proliferation of arterial smooth muscle cells (SMCs) and their modulation to alternative mesenchymal phenotypes is central to atherosclerotic lesion growth. It has been studied extensively in mouse models, but a detailed analysis of when and wh... read more
Bulletin of environmental contamination and toxicology
Jan 19, 2026
Per- and polyfluoroalkyl substances (PFAS) are environmentally persistent pollutants, posing challenges for effective remediation. This study presented a machine learning (ML) framework to predict the first-order reaction rate constant (k) of PFAS de... read more
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
Jan 19, 2026
BACKGROUND: Sarcopenia, characterized by progressive skeletal muscle loss, is associated with poor outcomes in various diseases. Traditional methods for assessing muscle cross-sectional area using computed tomography (CT) scans are manual, time-consu... read more
BACKGROUND: Radiation dose reduction is essential in paediatric lung computed tomography (CT). Advances in energy-integrating detector CT and deep-learning reconstruction may enable ultra-low-dose imaging comparable to photon-counting CT. OBJECTIVE: ... read more
OBJECTIVE: This study aims to both develop and evaluate a predictive model for ureteral access sheath(UAS)placement success using preoperative CT-based 3D ureteral imaging and machine learning techniques. Specifically, it investigates the impact of u... read more
European journal of clinical pharmacology
Jan 19, 2026
PURPOSE: The primary purpose of this study is to systematically evaluate how accurately artificial intelligence (AI) models can predict optimal warfarin dosing by incorporating both genetic variations-particularly in VKORC1 and CYP2C9-and clinical pa... read more
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