Exploring Heterogeneity in the Cost-Effectiveness of High-Flow Nasal Cannula Therapy in Acutely Ill Children-Insights From the Step-Up First-line Support for Assistance in Breathing in Children Trial Using a Machine Learning Method.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
PMID:

Abstract

OBJECTIVES: To investigate heterogeneity in the cost-effectiveness of high-flow nasal cannula (HFNC) therapy compared with continuous positive airway pressure (CPAP) for acutely ill children requiring noninvasive respiratory support.

Authors

  • Zaid Hattab
    Discipline of Economics, University of Galway, Galway, Ireland.
  • Silvia Moler-Zapata
    Department of Mathematics, An-Najah National University, Nablus, State of Palestine; Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, England, UK.
  • Edel Doherty
    Discipline of Economics, University of Galway, Galway, Ireland.
  • Zia Sadique
    Department of Health Services Research and Policy, London School of Hygiene & Tropical Medicine, London, UK.
  • Padmanabhan Ramnarayan
    Section of Anaesthetics, Pain Medicine, and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.
  • Stephen O'Neill
    Department of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK; Queen's University, Belfast, UK.