Predicting the molecular subtypes of 2021 WHO grade 4 glioma by a multiparametric MRI-based machine learning model.

Journal: BMC cancer
Published Date:

Abstract

BACKGROUND: Accurately distinguishing the different molecular subtypes of 2021 World Health Organization (WHO) grade 4 Central Nervous System (CNS) gliomas is highly relevant for prognostic stratification and personalized treatment.

Authors

  • Wenji Xu
    College of Medical Imaging, Shanxi Medical University, Taiyuan, 030001, Shanxi Province, China.
  • Yangyang Li
    Institute of Urology, The Third Affiliated Hospital of Shenzhen University, Shenzhen, 518000, P. R. China.
  • Jie Zhang
    College of Physical Education and Health, Linyi University, Linyi, Shandong, China.
  • Zhiyi Zhang
    Department of Epidemiology and Medical Statistics School of Public Health, Guangdong Medical University, Dongguan, Guangdong, China.
  • Pengxin Shen
    College of Medical Imaging, Shanxi Medical University, Taiyuan, 030001, Shanxi Province, China.
  • Xiaochun Wang
    Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
  • Guoqiang Yang
    School of Software, Shanxi Agricultural University, Jinzhong 030801, China.
  • Jiangfeng Du
    Department of Radiology, First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi Province, China.
  • Hui Zhang
    Department of Pulmonary Vessel and Thrombotic Disease, Sixth Medical Center, Chinese PLA General Hospital, Beijing, China.
  • Yan Tan
    Civil Aviation Flight University of China, Guanghan, 618300, China.