Unsupervised consensus cluster analysis of [18F]-fluoroethyl-L-tyrosine positron emission tomography identified textural features for the diagnosis of pseudoprogression in high-grade glioma.
Journal:
Oncotarget
Published Date:
Jan 31, 2017
Abstract
RATIONALE: Timely detection of pseudoprogression (PSP) is crucial for the management of patients with high-grade glioma (HGG) but remains difficult. Textural features of O-(2-[18F]fluoroethyl)-L-tyrosine positron emission tomography (FET-PET) mirror tumor uptake heterogeneity; some of them may be associated with tumor progression.
Authors
Keywords
Adult
Aged
Brain Neoplasms
Cluster Analysis
Disease Progression
Disease-Free Survival
Female
Glioma
Humans
Kaplan-Meier Estimate
Magnetic Resonance Imaging
Male
Middle Aged
Neoplasm Grading
Pilot Projects
Positron Emission Tomography Computed Tomography
Predictive Value of Tests
Radiographic Image Interpretation, Computer-Assisted
Radiopharmaceuticals
Reproducibility of Results
Retrospective Studies
Time Factors
Treatment Outcome
Tyrosine
Unsupervised Machine Learning