Combinatorial chemistry & high throughput screening
Jan 1, 2023
IMPORTANCE: Accurate pre-treatment prediction of distant metastasis in patients with Nasopharyngeal Carcinoma (NPC) enables the implementation of appropriate treatment strategies for high-risk individuals.
Combinatorial chemistry & high throughput screening
Jan 1, 2023
BACKGROUND: Osteoporosis is a prevalent disease for the aged population. Chinese herbderived natural compounds have anti-osteoporosis effects. Due to the complexity of chemical ingredients and natural products, it is necessary to develop a high-throu...
Combinatorial chemistry & high throughput screening
Jan 1, 2023
BACKGROUND: Ningnanmycin is a new antibiotic pesticide with good bactericidal and antiviral efficacy, which is widely used in the control of fruit and vegetable diseases, and the excessive pesticide residues pose a serious threat to the environment a...
Combinatorial chemistry & high throughput screening
Jan 1, 2023
With the continuous development of structural biology, the requirement for accurate threedimensional structures during functional modulation of biological macromolecules is increasing. Therefore, determining the dynamic structures of bio-macromolecul...
Combinatorial chemistry & high throughput screening
Jan 1, 2022
BACKGROUND: The process of nucleotides modification or methyl groups addition to nucleotides is known as post-transcriptional modification (PTM). 1-methyladenosine (m1A) is a type of PTM formed by adding a methyl group to the nitrogen at the 1st posi...
Combinatorial chemistry & high throughput screening
Jan 1, 2022
Cancer is a vast form of the disease that can begin in almost any organ or tissue of the body when abnormal cells grow uncontrollably and attack nearby organs. The traditional approaches to cancer diagnosis and drug development have certain limitatio...
Combinatorial chemistry & high throughput screening
Jan 1, 2022
The modern pharmaceutical industry is transitioning from traditional methods to advanced technologies like artificial intelligence. In the current scenario, continuous efforts are being made to incorporate computational modeling and simulation in dru...
Combinatorial chemistry & high throughput screening
Jan 1, 2022
The advancement of computing and technology has invaded all the dimensions of science. Artificial intelligence (AI) is one core branch of Computer Science, which has percolated to all the arenas of science and technology, from core engineering to med...
Combinatorial chemistry & high throughput screening
Jan 1, 2022
BACKGROUND AND OBJECTIVE: Blood pressure is vital evidence for clinicians to predict diseases and check the curative effect of diagnosis and treatment. To further improve the prediction accuracy of blood pressure, this paper proposes a combined predi...
Combinatorial chemistry & high throughput screening
Jan 1, 2022
INTRODUCTION: Drug repositioning aims to screen drugs and therapeutic goals from approved drugs and abandoned compounds that have been identified as safe. This trend is changing the landscape of drug development and creating a model of drug repositio...