AIMC Topic: Algorithms

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Deep Learning in Medical Image Analysis.

Annual review of biomedical engineering
This review covers computer-assisted analysis of images in the field of medical imaging. Recent advances in machine learning, especially with regard to deep learning, are helping to identify, classify, and quantify patterns in medical images. At the ...

predCar-site: Carbonylation sites prediction in proteins using support vector machine with resolving data imbalanced issue.

Analytical biochemistry
The carbonylation is found as an irreversible post-translational modification and considered a biomarker of oxidative stress. It plays major role not only in orchestrating various biological processes but also associated with some diseases such as Al...

Deep Learning Segmentation of Optical Microscopy Images Improves 3-D Neuron Reconstruction.

IEEE transactions on medical imaging
Digital reconstruction, or tracing, of 3-D neuron structure from microscopy images is a critical step toward reversing engineering the wiring and anatomy of a brain. Despite a number of prior attempts, this task remains very challenging, especially w...

Classification of toxicity effects of biotransformed hepatic drugs using whale optimized support vector machines.

Journal of biomedical informatics
Measuring toxicity is an important step in drug development. Nevertheless, the current experimental methods used to estimate the drug toxicity are expensive and time-consuming, indicating that they are not suitable for large-scale evaluation of drug ...

Embedding of semantic predications.

Journal of biomedical informatics
This paper concerns the generation of distributed vector representations of biomedical concepts from structured knowledge, in the form of subject-relation-object triplets known as semantic predications. Specifically, we evaluate the extent to which a...

Crystal Structure Representation for Neural Networks using Topological Approach.

Molecular informatics
In the present work we describe a new approach, which uses topology of crystals for physicochemical properties prediction using artificial neural networks (ANN). The topologies of 268 crystal structures were determined using ToposPro software. Quotie...

A Dataset and a Technique for Generalized Nuclear Segmentation for Computational Pathology.

IEEE transactions on medical imaging
Nuclear segmentation in digital microscopic tissue images can enable extraction of high-quality features for nuclear morphometrics and other analysis in computational pathology. Conventional image processing techniques, such as Otsu thresholding and ...

Dynamics of complex-valued fractional-order neural networks.

Neural networks : the official journal of the International Neural Network Society
The dynamics of complex-valued fractional-order neuronal networks are investigated, focusing on stability, instability and Hopf bifurcations. Sufficient conditions for the asymptotic stability and instability of a steady state of the network are deri...

Machine Learning of Global Phosphoproteomic Profiles Enables Discrimination of Direct versus Indirect Kinase Substrates.

Molecular & cellular proteomics : MCP
Mass spectrometry allows quantification of tens of thousands of phosphorylation sites from minute amounts of cellular material. Despite this wealth of information, our understanding of phosphorylation-based signaling is limited, in part because it is...

A novel computer-aided diagnosis system for breast MRI based on feature selection and ensemble learning.

Computers in biology and medicine
Breast cancer is a common cancer among women. With the development of modern medical science and information technology, medical imaging techniques have an increasingly important role in the early detection and diagnosis of breast cancer. In this pap...