AIMC Topic: Amyloid beta-Protein Precursor

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G-Protein Signaling in Alzheimer's Disease: Spatial Expression Validation of Semi-supervised Deep Learning-Based Computational Framework.

The Journal of neuroscience : the official journal of the Society for Neuroscience Nov 6, 2024
Systemic study of pathogenic pathways and interrelationships underlying genes associated with Alzheimer's disease (AD) facilitates the identification of new targets for effective treatments. Recently available large-scale multiomics datasets provide ...
Humans Brain Female Animals Male Deep Learning Protein Interaction Maps Mice Computational Biology Signal Transduction Supervised Machine Learning Alzheimer Disease Mice, Transgenic GTP-Binding Proteins Amyloid beta-Protein Precursor
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Machine learning reveals prominent spontaneous behavioral changes and treatment efficacy in humanized and transgenic Alzheimer's disease models.

Cell reports Oct 19, 2024
Computer-vision and machine-learning (ML) approaches are being developed to provide scalable, unbiased, and sensitive methods to assess mouse behavior. Here, we used the ML-based variational animal motion embedding (VAME) segmentation platform to ass...
Humans Machine Learning Female Animals Male Mice Treatment Outcome Disease Models, Animal Mice, Inbred C57BL Alzheimer Disease Behavior, Animal Mice, Transgenic Amyloid beta-Protein Precursor
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