AIMC Topic: Antigens, Viral

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Introducing of an integrated artificial neural network and Chou's pseudo amino acid composition approach for computational epitope-mapping of Crimean-Congo haemorrhagic fever virus antigens.

International immunopharmacology Nov 24, 2019
This study was aimed to introduce a novel algorithm for determining linear B- and T-cell epitopes from Crimean-Congo haemorrhagic fever virus (CCHFV) antigens. To this end, 387 approved B- and T-cell epitopes, as well as 331 non-epitope peptides from...
Hemorrhagic Fever, Crimean Epitope Mapping Hemorrhagic Fever Virus, Crimean-Congo Epitopes, B-Lymphocyte Molecular Docking Simulation Computational Biology Peptide Library Neural Networks, Computer Epitopes, T-Lymphocyte Humans Antigens, Viral Support Vector Machine Amino Acid Sequence Viral Proteins Histocompatibility Antigens Class II Protein Structure, Tertiary Datasets as Topic
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An inactivated influenza D virus vaccine partially protects cattle from respiratory disease caused by homologous challenge.

Veterinary microbiology Dec 21, 2016
Originally isolated from swine, the proposed influenza D virus has since been shown to be common in cattle. Inoculation of IDV to naïve calves resulted in mild respiratory disease histologically characterized by tracheitis. As several studies have as...
Vaccines, Inactivated Cattle Viral Vaccines Antigens, Viral Cattle Diseases Vaccination Viral Load Thogotovirus Antibodies, Viral Animals Orthomyxoviridae Infections Virus Shedding Bovine Respiratory Disease Complex
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Analysis of protein determinants of genotype-specific properties of group a rotaviruses using machine learning.

Computers in biology and medicine Jun 1, 2025
Group A rotaviruses (RVAs) are the leading cause of viral diarrhoea across various host species, including mammals and birds. The VP7 and VP4 proteins of these viruses play critical roles in determining genotype specificity, influencing viral infecti...
Animals Genotype Machine Learning Antigens, Viral Capsid Proteins Humans Rotavirus Infections Rotavirus
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Vaxign2: the second generation of the first Web-based vaccine design program using reverse vaccinology and machine learning.

Nucleic acids research Jul 2, 2021
Vaccination is one of the most significant inventions in medicine. Reverse vaccinology (RV) is a state-of-the-art technique to predict vaccine candidates from pathogen's genome(s). To promote vaccine development, we updated Vaxign2, the first web-bas...
COVID-19 SARS-CoV-2 Software Spike Glycoprotein, Coronavirus Proteome COVID-19 Vaccines Drug Design Machine Learning Humans Antigens, Viral Vaccines Vaccinology Internet Workflow Epitopes
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