AIMC Topic: Viral Vaccines
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Assessment of the transmission of live-attenuated chikungunya virus vaccine VLA1553 by Aedes albopictus mosquitoes.
Parasites & vectors
May 12, 2025
BACKGROUND: Chikungunya virus (CHIKV) is a mosquito-transmitted, arthritogenic alphavirus that causes sporadic outbreaks of often debilitating rheumatic disease. The recently approved CHIKV vaccine, IXCHIQ, is based on a live-attenuated CHIKV strain ...
Pathogenicity and virulence of lumpy skin disease virus: A comprehensive update.
Virulence
Apr 27, 2025
Lumpy skin disease (LSD), which was confined to the Africa for many decades, has expanded its geographical distribution to numerous countries across Asia and Europe in recent years. The LSD virus (LSDV) is a relatively poorly studied virus. Its 151 K...
Systematic collection, annotation, and pattern analysis of viral vaccines in the VIOLIN vaccine knowledgebase.
Frontiers in cellular and infection microbiology
Feb 7, 2025
BACKGROUND: Viral vaccines have been proven significant in protecting us against viral diseases such as COVID-19. To better understand and design viral vaccines, it is critical to systematically collect, annotate, and analyse various viral vaccines a...
Experimental validation of immunogenic SARS-CoV-2 T cell epitopes identified by artificial intelligence.
Frontiers in immunology
Nov 17, 2023
During the COVID-19 pandemic we utilized an AI-driven T cell epitope prediction tool, the NEC Immune Profiler (NIP) to scrutinize and predict regions of T cell immunogenicity (hotspots) from the entire SARS-CoV-2 viral proteome. These immunogenic reg...
Identification of vaccine targets & design of vaccine against SARS-CoV-2 coronavirus using computational and deep learning-based approaches.
PeerJ
May 19, 2022
An unusual pneumonia infection, named COVID-19, was reported on December 2019 in China. It was reported to be caused by a novel coronavirus which has infected approximately 220 million people worldwide with a death toll of 4.5 million as of September...
A Novel Strategy for the Development of Vaccines for SARS-CoV-2 (COVID-19) and Other Viruses Using AI and Viral Shell Disorder.
Journal of proteome research
Oct 2, 2020
A model that predicts levels of coronavirus (CoV) respiratory and fecal-oral transmission potentials based on the shell disorder has been built using neural network (artificial intelligence, AI) analysis of the percentage of disorder (PID) in the nuc...
Evolutionary artificial intelligence based peptide discoveries for effective Covid-19 therapeutics.
Biochimica et biophysica acta. Molecular basis of disease
Sep 24, 2020
An epidemic caused by COVID-19 in China turned into pandemic within a short duration affecting countries worldwide. Researchers and companies around the world are working on all the possible strategies to develop a curative or preventive strategy for...
The combination of artificial intelligence and systems biology for intelligent vaccine design.
Expert opinion on drug discovery
Jul 14, 2020
INTRODUCTION: A new body of evidence depicts the applications of artificial intelligence and systems biology in vaccine design and development. The combination of both approaches shall revolutionize healthcare, accelerating clinical trial processes a...
COVID-19 Coronavirus Vaccine Design Using Reverse Vaccinology and Machine Learning.
Frontiers in immunology
Jul 3, 2020
To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. Our literature and clinical trial survey showed that the whole vi...
Artificial Intelligence (AI) applications for COVID-19 pandemic.
Diabetes & metabolic syndrome
Apr 14, 2020
BACKGROUND AND AIMS: Healthcare delivery requires the support of new technologies like Artificial Intelligence (AI), Internet of Things (IoT), Big Data and Machine Learning to fight and look ahead against the new diseases. We aim to review the role o...
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