AIMC Topic: Bayes Theorem

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Assessing hERG1 Blockade from Bayesian Machine-Learning-Optimized Site Identification by Ligand Competitive Saturation Simulations.

Journal of chemical information and modeling
Drug-induced cardiotoxicity is a potentially lethal and yet one of the most common side effects with the drugs in clinical use. Most of the drug-induced cardiotoxicity is associated with an off-target pharmacological blockade of K currents carried ou...

Can We Ditch Feature Engineering? End-to-End Deep Learning for Affect Recognition from Physiological Sensor Data.

Sensors (Basel, Switzerland)
To further extend the applicability of wearable sensors in various domains such as mobile health systems and the automotive industry, new methods for accurately extracting subtle physiological information from these wearable sensors are required. How...

A Benchmark of Data Stream Classification for Human Activity Recognition on Connected Objects.

Sensors (Basel, Switzerland)
This paper evaluates data stream classifiers from the perspective of connected devices, focusing on the use case of Human Activity Recognition. We measure both the classification performance and resource consumption (runtime, memory, and power) of fi...

Machine Learning Methods in Drug Discovery.

Molecules (Basel, Switzerland)
The advancements of information technology and related processing techniques have created a fertile base for progress in many scientific fields and industries. In the fields of drug discovery and development, machine learning techniques have been use...

Repurposing therapeutics for COVID-19: Rapid prediction of commercially available drugs through machine learning and docking.

PloS one
BACKGROUND: The outbreak of the novel coronavirus disease COVID-19, caused by the SARS-CoV-2 virus has spread rapidly around the globe during the past 3 months. As the virus infected cases and mortality rate of this disease is increasing exponentiall...

Differentiation of low and high grade renal cell carcinoma on routine MRI with an externally validated automatic machine learning algorithm.

Scientific reports
Pre-treatment determination of renal cell carcinoma aggressiveness may help guide clinical decision-making. We aimed to differentiate low-grade (Fuhrman I-II) from high-grade (Fuhrman III-IV) renal cell carcinoma using radiomics features extracted fr...

Closing the Digital Health Evidence Gap: Development of a Predictive Score to Maximize Patient Outcomes.

Telemedicine journal and e-health : the official journal of the American Telemedicine Association
Clinical studies of telemedicine (TM) programs for chronic illness have demonstrated mixed results across settings and populations. With recent uptake in use of digital health modalities, more precise patient classification may improve outcomes, eff...

Classification of Aggressive Movements Using Smartwatches.

Sensors (Basel, Switzerland)
Recognizing aggressive movements is a challenging task in human activity recognition. Wearable smartwatch technology with machine learning may be a viable approach for human aggressive behavior classification. This research identified a viable classi...

LDA filter: A Latent Dirichlet Allocation preprocess method for Weka.

PloS one
This work presents an alternative method to represent documents based on LDA (Latent Dirichlet Allocation) and how it affects to classification algorithms, in comparison to common text representation. LDA assumes that each document deals with a set o...

Comprehensive Study on Molecular Supervised Learning with Graph Neural Networks.

Journal of chemical information and modeling
This work considers strategies to develop accurate and reliable graph neural networks (GNNs) for molecular property predictions. Prediction performance of GNNs is highly sensitive to the change in various parameters due to the inherent challenges in ...