AIMC Topic: Biofilms
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Chemical multiscale robotics for bacterial biofilm treatment.
Chemical Society reviews
Mar 4, 2024
A biofilm constitutes a bacterial community encased in a sticky matrix of extracellular polymeric substances. These intricate microbial communities adhere to various host surfaces such as hard and soft tissues as well as indwelling medical devices. T...
inhibition of biofilm and virulence factor production in azole-resistant strains of isolated from diabetic foot by stabilized tin (IV) oxide nanoparticles.
Frontiers in cellular and infection microbiology
Jan 25, 2024
The advent of nanotechnology has been instrumental in the development of new drugs with novel targets. Recently, metallic nanoparticles have emerged as potential candidates to combat the threat of drug-resistant infections. Diabetic foot ulcers (DFUs...
Investigating the bispecific lead compounds against methicillin-resistant SarA and CrtM using machine learning and molecular dynamics approach.
Journal of biomolecular structure & dynamics
Dec 26, 2023
Methicillin-resistant Staphylococcus aureus (MRSA) is a notorious pathogen that has emerged as a serious global health concern over the past few decades. Staphylococcal accessory regulator A (SarA) and 4,4'-diapophytoene synthase (CrtM) play a crucia...
Antimicrobial Activity of Extract Used for Potential Application in the Prevention and Treatment of Oral Diseases.
Medicina (Kaunas, Lithuania)
Dec 21, 2023
: This study evaluated the antimicrobial effect and cytotoxic potential of the natural extract against (), the causative agent of dental caries, which is a typical oral disease, and (), which causes oral candidiasis. : was shaken in 70% ethanol f...
Magnetic Soft Robot for Minimally Invasive Urethral Catheter Biofilm Eradication.
ACS nano
Oct 23, 2023
Catheter-related biofilm infection remains the main problem for millions of people annually, affecting morbidity, mortality, and quality of life. Despite the recent advances in the prevention of biofilm formation, alternative methods for biofilm prev...
Electrochemical Impedance Spectroscopy-Based Sensing of Biofilms: A Comprehensive Review.
Biosensors
Jul 31, 2023
Biofilms are complex communities of microorganisms that can form on various surfaces, including medical devices, industrial equipment, and natural environments. The presence of biofilms can lead to a range of problems, including infections, reduced e...
Anti-Biofilm: Machine Learning Assisted Prediction of IC Activity of Chemicals Against Biofilms of Microbes Causing Antimicrobial Resistance and Implications in Drug Repurposing.
Journal of molecular biology
Apr 20, 2023
Biofilms are one of the leading causes of antibiotic resistance. It acts as a physical barrier against the human immune system and drugs. The use of anti-biofilm agents helps in tackling the menace of antibiotic resistance. The identification of effi...
Single-cell segmentation in bacterial biofilms with an optimized deep learning method enables tracking of cell lineages and measurements of growth rates.
Molecular microbiology
Apr 17, 2023
Bacteria often grow into matrix-encased three-dimensional (3D) biofilm communities, which can be imaged at cellular resolution using confocal microscopy. From these 3D images, measurements of single-cell properties with high spatiotemporal resolution...
Artificial Intelligence-Driven Image Analysis of Bacterial Cells and Biofilms.
IEEE/ACM transactions on computational biology and bioinformatics
Feb 3, 2023
The current study explores an artificial intelligence framework for measuring the structural features from microscopy images of the bacterial biofilms. Desulfovibrio alaskensis G20 (DA-G20) grown on mild steel surfaces is used as a model for sulfate ...
Automatic dental biofilm detection based on deep learning.
Journal of clinical periodontology
Jan 25, 2023
AIM: To estimate the automated biofilm detection capacity of the U-Net neural network on tooth images.
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