AIMC Topic: Biological Ontologies
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Generation of open biomedical datasets through ontology-driven transformation and integration processes.
Journal of biomedical semantics
Jun 3, 2016
BACKGROUND: Biomedical research usually requires combining large volumes of data from multiple heterogeneous sources, which makes difficult the integrated exploitation of such data. The Semantic Web paradigm offers a natural technological space for d...
Ontology-based collection, representation and analysis of drug-associated neuropathy adverse events.
Journal of biomedical semantics
May 21, 2016
BACKGROUND: Neuropathy often occurs following drug treatment such as chemotherapy. Severe instances of neuropathy can result in cessation of life-saving chemotherapy treatment.
The cellular microscopy phenotype ontology.
Journal of biomedical semantics
May 18, 2016
BACKGROUND: Phenotypic data derived from high content screening is currently annotated using free-text, thus preventing the integration of independent datasets, including those generated in different biological domains, such as cell lines, mouse and ...
An ontological model of the practice transformation process.
Journal of biomedical informatics
May 10, 2016
Patient-centered medical home is defined as an approach for providing comprehensive primary care that facilitates partnerships between individual patients and their personal providers. The current state of the practice transformation process is ad ho...
Publication of nuclear magnetic resonance experimental data with semantic web technology and the application thereof to biomedical research of proteins.
Journal of biomedical semantics
May 5, 2016
BACKGROUND: The nuclear magnetic resonance (NMR) spectroscopic data for biological macromolecules archived at the BioMagResBank (BMRB) provide a rich resource of biophysical information at atomic resolution. The NMR data archived in NMR-STAR ASCII fo...
The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology.
Journal of biomedical semantics
May 4, 2016
In recent years, sequencing technologies have enabled the identification of a wide range of non-coding RNAs (ncRNAs). Unfortunately, annotation and integration of ncRNA data has lagged behind their identification. Given the large quantity of informat...
OBIB-a novel ontology for biobanking.
Journal of biomedical semantics
May 2, 2016
BACKGROUND: Biobanking necessitates extensive integration of data to allow data analysis and specimen sharing. Ontologies have been demonstrated to be a promising approach in fostering better semantic integration of biobank-related data. Hitherto no ...
Collective intelligence in medical diagnosis systems: A case study.
Computers in biology and medicine
Apr 29, 2016
Diagnosing a patient's condition is one of the most important and challenging tasks in medicine. We present a study of the application of collective intelligence in medical diagnosis by applying consensus methods. We compared the accuracy obtained wi...
miRiaD: A Text Mining Tool for Detecting Associations of microRNAs with Diseases.
Journal of biomedical semantics
Apr 29, 2016
BACKGROUND: MicroRNAs are increasingly being appreciated as critical players in human diseases, and questions concerning the role of microRNAs arise in many areas of biomedical research. There are several manually curated databases of microRNA-diseas...
The Ontology for Biomedical Investigations.
PloS one
Apr 29, 2016
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide...
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