AIMC Topic: Biological Ontologies

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Semantic Web Ontology and Data Integration: a Case Study in Aiding Psychiatric Drug Repurposing.

Studies in health technology and informatics
There remain significant difficulties selecting probable candidate drugs from existing databases. We describe an ontology-oriented approach to represent the nexus between genes, drugs, phenotypes, symptoms, and diseases from multiple information sour...

Rule-based Cervical Spine Defect Classification Using Medical Narratives.

Studies in health technology and informatics
Classifying the defects occurring at the cervical spine provides the basis for surgical treatment planning and therapy recommendation. This process requires evidence from patient records. Further, the degree of a defect needs to be encoded in a stand...

Translating ICD-11 into French using lexical-based approach: a preliminary study.

Studies in health technology and informatics
To translate the 11th edition of the International Classification of Diseases (ICD-11) into French, we proposed a lexical approach using Natural Language Processing techniques. This method relies on the 56 biomedical terminologies and ontologies incl...

Extraction of Vital Signs from Clinical Notes.

Studies in health technology and informatics
Assessment of vital signs is an essential part of surveillance of critically ill patients to detect condition changes and clinical deterioration. While most modern electronic medical records allow for vitals to be recorded in a structured format, the...

Extracting Dependence Relations from Unstructured Medical Text.

Studies in health technology and informatics
Dependence relations among disease and risk factors are a key ingredient in risk modeling and decision support models. Currently such information is either provided by experts (costly and time consuming) or extracted from data (if available). The pub...

Development and evaluation of task-specific NLP framework in China.

Studies in health technology and informatics
Natural language processing (NLP) has been designed to convert narrative text into structured data. Although some general NLP architectures have been developed, a task-specific NLP framework to facilitate the effective use of data is still a challeng...

Ontology-Driven Semantic Search for Brazilian Portuguese Clinical Notes.

Studies in health technology and informatics
The emerging penetration of Health IT in Latin America (especially in Brazil) has exacerbated the ever-increasing amount of Electronic Health Record (EHR) clinical free text documents.This imposes a workflow efficiency challenge on clinicians who nee...

Harmonizing SNOMED CT with BioTopLite: An Exercise in Principled Ontology Alignment.

Studies in health technology and informatics
The integration of heterogeneous ontologies is often hampered by different upper level categories and relations. We report on an on-going effort to align clinical terminology/ontology SNOMED CT with the formal upper-level ontology BioTopLite. This al...

A Process for the Representation of openEHR ADL Archetypes in OWL Ontologies.

Studies in health technology and informatics
ADL is a formal language to express archetypes, independent of standards or domain. However, its specification is not precise enough in relation to the specialization and semantic of archetypes, presenting difficulties in implementation and a few ava...