AIMC Topic: Biology

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AlphaFold2 and its applications in the fields of biology and medicine.

Signal transduction and targeted therapy
AlphaFold2 (AF2) is an artificial intelligence (AI) system developed by DeepMind that can predict three-dimensional (3D) structures of proteins from amino acid sequences with atomic-level accuracy. Protein structure prediction is one of the most chal...

Collective computational intelligence in biology - Emergence of memory in somatic tissues.

Bio Systems
Role of memory in the function of biological tissues, organs and organisms remains unexplored with many unanswered questions. In this study, the emergence of associative memory in somatic (non-neural) tissues and its potential relation to tissue func...

Deep reinforcement learning for optimal experimental design in biology.

PLoS computational biology
The field of optimal experimental design uses mathematical techniques to determine experiments that are maximally informative from a given experimental setup. Here we apply a technique from artificial intelligence-reinforcement learning-to the optima...

Anatomy and the type concept in biology show that ontologies must be adapted to the diagnostic needs of research.

Journal of biomedical semantics
BACKGROUND: In times of exponential data growth in the life sciences, machine-supported approaches are becoming increasingly important and with them the need for FAIR (Findable, Accessible, Interoperable, Reusable) and eScience-compliant data and met...

Testing the reproducibility and robustness of the cancer biology literature by robot.

Journal of the Royal Society, Interface
Scientific results should not just be 'repeatable' (replicable in the same laboratory under identical conditions), but also 'reproducible' (replicable in other laboratories under similar conditions). Results should also, if possible, be 'robust' (rep...

Machine Learning at the Interface of Polymer Science and Biology: How Far Can We Go?

Biomacromolecules
This Perspective outlines recent progress and future directions for using machine learning (ML), a data-driven method, to address critical questions in the design, synthesis, processing, and characterization of . The achievement of these tasks requir...

Network biology and artificial intelligence drive the understanding of the multidrug resistance phenotype in cancer.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Globally with over 10 million deaths per year, cancer is the most transversal disease across countries, cultures, and ethnicities, affecting both developed and developing regions. Tumorigenesis is dynamically altered by distinct events and can be let...

AI revolutions in biology: The joys and perils of AlphaFold.

EMBO reports
AlphaFold is the most ground-breaking application of AI in science so far; it will revolutionize structural biology, but caution is warranted.

A guide to machine learning for biologists.

Nature reviews. Molecular cell biology
The expanding scale and inherent complexity of biological data have encouraged a growing use of machine learning in biology to build informative and predictive models of the underlying biological processes. All machine learning techniques fit models ...