AIMC Topic: Bradykinin

Clear Filters Showing 1 to 1 of 1 articles

Pharmacokinetics of single and repeat doses of icatibant.

Clinical pharmacology in drug development
PURPOSE: Icatibant is a bradykinin-2 receptor antagonist approved to treat acute hereditary angioedema attacks in adults. To-date, no thorough investigation of the clinical pharmacokinetic (PK) parameters of icatibant and its primary metabolites has ...