AIMC Topic: Caspase 3

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Astragalus Polysaccharide Inhibits Autophagy and Apoptosis from Peroxide-Induced Injury in C2C12 Myoblasts.

Cell biochemistry and biophysics Nov 1, 2015
The aim is to study the effects and underlying mechanisms of astragalus polysaccharide (APS) on the peroxide-induced injury in C2C12 myoblasts in vitro. Cell viability in the presence or absence of APS was detected by the methyl thiazolyl tetrazolium...
Animals Hydrogen Peroxide Mice Signal Transduction Apoptosis Cell Line Cell Survival Caspase 3 Blotting, Western Autophagy TOR Serine-Threonine Kinases bcl-2-Associated X Protein Polysaccharides Proto-Oncogene Proteins c-bcl-2 Myoblasts Microscopy, Electron Microtubule-Associated Proteins Astragalus Plant Cytochromes c Ribosomal Protein S6 Kinases, 70-kDa
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Compressed images for affinity prediction-2 (CIFAP-2): an improved machine learning methodology on protein-ligand interactions based on a study on caspase 3 inhibitors.

Journal of enzyme inhibition and medicinal chemistry Jan 1, 2015
The aim of this study is to propose an improved computational methodology, which is called Compressed Images for Affinity Prediction-2 (CIFAP-2) to predict binding affinities of structurally related protein-ligand complexes. CIFAP-2 method is establi...
Humans Machine Learning Dose-Response Relationship, Drug Caspase 3 Regression Analysis Structure-Activity Relationship Molecular Structure Sulfonamides Ligands Enzyme Inhibitors
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