AIMC Topic: Myoblasts
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Clustering cell nuclei on microgrooves for disease diagnosis using deep learning.
Scientific reports
Jul 2, 2025
Various diseases including laminopathies and certain types of cancer are associated with abnormal nuclear mechanical properties that influence cellular and nuclear deformations in complex environments. Recently, microgroove substrates designed to mim...
Measuring alignment of structural proteins in engineered tissue constructs using polarized Raman spectroscopy.
PloS one
May 30, 2025
Measures of structural protein alignment within biological and engineered tissues are needed for improved understanding of their mechanical behavior and functionality. We advance our method of measuring protein alignment using polarized Raman spectro...
Multiview confocal super-resolution microscopy.
Nature
Nov 26, 2021
Confocal microscopy remains a major workhorse in biomedical optical microscopy owing to its reliability and flexibility in imaging various samples, but suffers from substantial point spread function anisotropy, diffraction-limited resolution, depth-d...
Metamorphosis in Insect Muscle: Insights for Engineering Muscle-Based Actuators.
Tissue engineering. Part B, Reviews
Nov 4, 2020
One of the major limitations to advancing the development of soft robots is the absence of lightweight, effective soft actuators. While synthetic systems, such as pneumatics and shape memory alloys, have created important breakthroughs in soft actuat...
A Coupled FEM-SPH Modeling Technique to Investigate the Contractility of Biohybrid Thin Films.
Advanced biosystems
Jun 9, 2020
Biohybrid actuators have the potential to overcome the limitations of traditional actuators employed in robotics, thanks to the unique features of living contractile muscle cells, which can be used to power artificial elements. This paper describes a...
Neuromuscular actuation of biohybrid motile bots.
Proceedings of the National Academy of Sciences of the United States of America
Sep 16, 2019
The integration of muscle cells with soft robotics in recent years has led to the development of biohybrid machines capable of untethered locomotion. A major frontier that currently remains unexplored is neuronal actuation and control of such muscle-...
Regulation of C2C12 Differentiation and Control of the Beating Dynamics of Contractile Cells for a Muscle-Driven Biosyncretic Crawler by Electrical Stimulation.
Soft robotics
Oct 18, 2018
Biosyncretic robots have potential advantages associated with both living organisms and electromechanical systems. Skeletal muscle tissue is a candidate as bioactuators for biosyncretic robots because of its excellent contraction force and controllab...
Anticancer activity of biologically synthesized silver and gold nanoparticles on mouse myoblast cancer cells and their toxicity against embryonic zebrafish.
Materials science & engineering. C, Materials for biological applications
Dec 23, 2016
The aim of this study was to evaluate the anticancer activity of bioinspired silver nanoparticles (AgNPs) and gold nanoparticles (AuNPs) against mouse myoblast cancer cells (CC). Both AgNPs and AuNPs were biologically synthesized using Spinacia olera...
Photoacoustic Techniques
Spinacia oleracea
Embryo, Nonmammalian
Acridine Orange
Staining and Labeling
Cell Shape
Plant Extracts
Ethidium
Zebrafish
Apoptosis
Caspases
Animals
Plant Leaves
Cell Survival
Myoblasts
Antineoplastic Agents
Gold
Toxicity Tests
Cell Line, Tumor
Metal Nanoparticles
X-Ray Diffraction
Silver
Mice
aqueous extract attenuates isoproterenol-induced cardiac hypertrophy through the ERK signalling pathway.
Pharmaceutical biology
Dec 1, 2020
CONTEXT: The pharmacological functions of Wall. ex Lindl. (Orchidaceae) in cardiac hypertrophy remains unclear.
Astragalus Polysaccharide Inhibits Autophagy and Apoptosis from Peroxide-Induced Injury in C2C12 Myoblasts.
Cell biochemistry and biophysics
Nov 1, 2015
The aim is to study the effects and underlying mechanisms of astragalus polysaccharide (APS) on the peroxide-induced injury in C2C12 myoblasts in vitro. Cell viability in the presence or absence of APS was detected by the methyl thiazolyl tetrazolium...
Mice
Signal Transduction
Apoptosis
Cell Line
Blotting, Western
Autophagy
TOR Serine-Threonine Kinases
Cell Survival
Caspase 3
Animals
Hydrogen Peroxide
Microscopy, Electron
Microtubule-Associated Proteins
Astragalus Plant
bcl-2-Associated X Protein
Cytochromes c
Polysaccharides
Ribosomal Protein S6 Kinases, 70-kDa
Proto-Oncogene Proteins c-bcl-2
Myoblasts
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