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Cell Plasticity

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Morphological profiling using machine learning reveals emergent subpopulations of interferon-γ-stimulated mesenchymal stromal cells that predict immunosuppression.

Cytotherapy 30503100
BACKGROUND: Although a preponderance of pre-clinical data demonstrates the immunosuppressive potential of mesenchymal stromal cells (MSCs), significant heterogeneity and lack of critical quality attributes (CQAs) based on immunosuppressive capacity l...
CD4-Positive T-Lymphocytes CD8-Positive T-Lymphocytes Cell Plasticity Cell Proliferation Cells, Cultured Coculture Techniques Humans Immunosuppression Therapy Interferon-gamma Leukocytes, Mononuclear Lymphocyte Activation Machine Learning Mesenchymal Stem Cells Stochastic Processes Tissue Embedding
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