Stick insects exhibit remarkable adaptive walking capabilities across diverse environments; however, the mechanisms underlying their gait transitions remain poorly understood. Although reinforcement learning (RL) has been employed to generate insect-...
In response to the urgent issues faced by current bionic undulating fin robot propulsion mechanisms, such as low working efficiency, insufficient swimming speed, ignoring thickness parameters, and the need for further improvement in biomimetic degree...
Biological systems maintain stability of their function in spite of external and internal perturbations. An important challenge in studying biological regulation is to identify the control objectives based on empirical data. Very often these objectiv...
Proceedings of the National Academy of Sciences of the United States of America
Jun 4, 2025
Characterizing the conformational ensemble of biomolecular systems is key to understand their functions. Cryoelectron microscopy (cryo-EM) captures two-dimensional snapshots of biomolecular ensembles, giving in principle access to thermodynamics. How...
During walking and running, animals display rich and coordinated motor patterns that are generated and controlled within the central nervous system. Previous computational and experimental results suggest that the balance between excitation and inhib...
The inferential results regarding estimates of Support Vector Regression (SVR) are highly influenced by anomalies and ill-conditioned predictors. Excessive dimensions of data also make the model complex. To improve estimation accuracy, this paper int...
The accurate modeling of dynamic systems, particularly robotic ones, is crucial in the industry. It enables simulation-based approaches that facilitate various tasks without requiring the physical system, thereby reducing risks and costs. These appro...
The relationship between morphology and locomotion performance in amphibious fish remains poorly understood, particularly in axial-appendage-based and appendage-based movements. To address this, we introduce Polymander, a reconfigurable robot capable...
In the era of digitization, online digital advertising is one of the best techniques for modern marketing. This makes advertisers rely heavily on accurate user interest and behavior modelling to deliver precise advertisement impressions and increase ...
Engineered T-cell receptor (eTCR) systems rely on accurately generated T-cell receptor (TCR) sequences to enhance immunotherapy predictability and efficacy. The most variable and crucial part of the TCR receptor is the CDR3 sequence region. Current m...
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