The eyes possess sophisticated physiological structures, diverse disease targets, limited drug delivery space, distinctive barriers, and complicated biomechanical processes, requiring a more in-depth understanding of the interactions between drug del...
DNA nanotechnology is a rapidly developing field that uses DNA as a building material for nanoscale structures. Key to the field's development has been the ability to accurately describe the behavior of DNA nanostructures using simulations and other ...
Computational intelligence and neuroscience
Mar 7, 2023
Computational models of emotions can not only improve the effectiveness and efficiency of human-robot interaction but also coordinate a robot to adapt to its environment better. When designing computational models of emotions for socially interactive...
CPT: pharmacometrics & systems pharmacology
Mar 5, 2023
Artificial intelligence (AI) has come to be used in various technological fields in recent years. However, there have been no reports of AI-designed clinical trials. In this study, we tried to develop study designs by a genetic algorithm (GA), which ...
BACKGROUND: Applying deep learning to digital histopathology is hindered by the scarcity of manually annotated datasets. While data augmentation can ameliorate this obstacle, its methods are far from standardized. Our aim was to systematically explor...
IMPORTANCE: Many clinical trial outcomes are documented in free-text electronic health records (EHRs), making manual data collection costly and infeasible at scale. Natural language processing (NLP) is a promising approach for measuring such outcomes...
Basal ganglia (BG) are a widely recognized neural basis for action selection, but its decision-making mechanism is still a difficult problem for researchers. Therefore, we constructed a spiking neural network inspired by the BG anatomical data. Simul...
Car networking systems based on 5G-V2X (vehicle-to-everything) have high requirements for reliability and low-latency communication to further improve communication performance. In the V2X scenario, this article establishes an extended model (basic e...
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Feb 24, 2023
Calcium-activated chloride channels (CaCCs) are chloride channels that are regulated according to intracellular calcium ion concentrations. The channel protein ANO1 is widely present in cells and is involved in physiological activities including cell...
Machine learning methods are widely used within the medical field. However, the reliability and efficacy of these models is difficult to assess, making it difficult for researchers to identify which machine-learning model to apply to their dataset. W...