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Data Curation

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Moving the mountain: analysis of the effort required to transform comparative anatomy into computable anatomy.

Database : the journal of biological databases and curation
The diverse phenotypes of living organisms have been described for centuries, and though they may be digitized, they are not readily available in a computable form. Using over 100 morphological studies, the Phenoscape project has demonstrated that by...

The Confidence Information Ontology: a step towards a standard for asserting confidence in annotations.

Database : the journal of biological databases and curation
Biocuration has become a cornerstone for analyses in biology, and to meet needs, the amount of annotations has considerably grown in recent years. However, the reliability of these annotations varies; it has thus become necessary to be able to assess...

Ontology application and use at the ENCODE DCC.

Database : the journal of biological databases and curation
The Encyclopedia of DNA elements (ENCODE) project is an ongoing collaborative effort to create a catalog of genomic annotations. To date, the project has generated over 4000 experiments across more than 350 cell lines and tissues using a wide array o...

Shared resources, shared costs--leveraging biocuration resources.

Database : the journal of biological databases and curation
The manual curation of the information in biomedical resources is an expensive task. This article argues the value of this approach in comparison with other apparently less costly options, such as automated annotation or text-mining, then discusses w...

mycoCLAP, the database for characterized lignocellulose-active proteins of fungal origin: resource and text mining curation support.

Database : the journal of biological databases and curation
Enzymes active on components of lignocellulosic biomass are used for industrial applications ranging from food processing to biofuels production. These include a diverse array of glycoside hydrolases, carbohydrate esterases, polysaccharide lyases and...

Combining computational models, semantic annotations and simulation experiments in a graph database.

Database : the journal of biological databases and curation
Model repositories such as the BioModels Database, the CellML Model Repository or JWS Online are frequently accessed to retrieve computational models of biological systems. However, their storage concepts support only restricted types of queries and ...

Regular expression-based learning to extract bodyweight values from clinical notes.

Journal of biomedical informatics
BACKGROUND: Bodyweight related measures (weight, height, BMI, abdominal circumference) are extremely important for clinical care, research and quality improvement. These and other vitals signs data are frequently missing from structured tables of ele...

Domain adaption of parsing for operative notes.

Journal of biomedical informatics
BACKGROUND: Full syntactic parsing of clinical text as a part of clinical natural language processing (NLP) is critical for a wide range of applications. Several robust syntactic parsers are publicly available to produce linguistic representations fo...

EcoliNet: a database of cofunctional gene network for Escherichia coli.

Database : the journal of biological databases and curation
During the past several decades, Escherichia coli has been a treasure chest for molecular biology. The molecular mechanisms of many fundamental cellular processes have been discovered through research on this bacterium. Although much basic research n...

An ontology-based annotation of cardiac implantable electronic devices to detect therapy changes in a national registry.

IEEE journal of biomedical and health informatics
The patient population benefitting from cardiac implantable electronic devices (CIEDs) is increasing. This study introduces a device annotation method that supports the consistent description of the functional attributes of cardiac devices and evalua...