Journal of biomedical informatics
Jul 26, 2015
Databases of curated biomedical knowledge, such as the protein-locations reflected in the UniProtKB database, provide an accurate and useful resource to researchers and decision makers. Our goal is to augment the manual efforts currently used to cura...
Database : the journal of biological databases and curation
May 13, 2015
The diverse phenotypes of living organisms have been described for centuries, and though they may be digitized, they are not readily available in a computable form. Using over 100 morphological studies, the Phenoscape project has demonstrated that by...
Database : the journal of biological databases and curation
May 9, 2015
Biocuration has become a cornerstone for analyses in biology, and to meet needs, the amount of annotations has considerably grown in recent years. However, the reliability of these annotations varies; it has thus become necessary to be able to assess...
Database : the journal of biological databases and curation
Mar 16, 2015
The Encyclopedia of DNA elements (ENCODE) project is an ongoing collaborative effort to create a catalog of genomic annotations. To date, the project has generated over 4000 experiments across more than 350 cell lines and tissues using a wide array o...
Database : the journal of biological databases and curation
Mar 16, 2015
The manual curation of the information in biomedical resources is an expensive task. This article argues the value of this approach in comparison with other apparently less costly options, such as automated annotation or text-mining, then discusses w...
Database : the journal of biological databases and curation
Mar 8, 2015
Enzymes active on components of lignocellulosic biomass are used for industrial applications ranging from food processing to biofuels production. These include a diverse array of glycoside hydrolases, carbohydrate esterases, polysaccharide lyases and...
Database : the journal of biological databases and curation
Mar 8, 2015
Model repositories such as the BioModels Database, the CellML Model Repository or JWS Online are frequently accessed to retrieve computational models of biological systems. However, their storage concepts support only restricted types of queries and ...
Journal of biomedical informatics
Mar 5, 2015
BACKGROUND: Bodyweight related measures (weight, height, BMI, abdominal circumference) are extremely important for clinical care, research and quality improvement. These and other vitals signs data are frequently missing from structured tables of ele...
Journal of biomedical informatics
Feb 7, 2015
BACKGROUND: Full syntactic parsing of clinical text as a part of clinical natural language processing (NLP) is critical for a wide range of applications. Several robust syntactic parsers are publicly available to produce linguistic representations fo...
Database : the journal of biological databases and curation
Feb 2, 2015
During the past several decades, Escherichia coli has been a treasure chest for molecular biology. The molecular mechanisms of many fundamental cellular processes have been discovered through research on this bacterium. Although much basic research n...