Peptides are ubiquitous and important biomolecules that self-assemble into diverse structures. Although extensive research has explored the effects of chemical composition and exterior conditions on self-assembly, a systematic study consolidating the...
Pharmacokinetic (PK) models are essential for optimising drug candidate selection and dosing regimens in drug development. Preclinical and population PK models benefit from integrating prior knowledge from existing compounds. While tables in scientif...
BACKGROUND: Neuralgia and other neuropathic pain are difficult to treat owing to their complicated etiology and a wide variety of responses to treatment. The novel neuromodulation technology transcranial focused ultrasound (tFUS) has intriguing impli...
Fall-from-height (FFH) accidents remain a major source of workplace injuries and fatalities. Fall protection systems (FPS) are critical for preventing falls in the work-at-height (WAH) environment. However, challenges in designing and selecting effec...
The revolution of artificial intelligence (AI) methods in the scope of the last years has inspired a deluge of use cases but has also caused uncertainty about the actual utility and boundaries of these methods. In this overview, we briefly introduce ...
BMC medical informatics and decision making
Mar 17, 2025
BACKGROUND: The HELLP syndrome represents three complications: hemolysis, elevated liver enzymes, and low platelet count. Since the causes and pathogenesis of HELLP syndrome are not yet fully known and well understood, distinguishing it from other pr...
Manually converting unstructured text pathology reports into structured pathology reports is very time-consuming and prone to errors. This study demonstrates the transformative potential of generative AI in automating the analysis of free-text pathol...
BMC medical informatics and decision making
Mar 7, 2025
BACKGROUND: Retinal vein occlusion (RVO) is a leading cause of vision loss globally. Routine health check-up data-including demographic information, medical history, and laboratory test results-are commonly utilized in clinical settings for disease r...
OBJECTIVE: As one of the most crucial upstream tasks in biomedical informatics, biomedical named entity normalization (BNEN) aims to map mentioned named entities to uniform standard identifiers or terms. Most existing methods only consider the simila...
BACKGROUND: Patients' oral expressions serve as valuable sources of clinical information to improve pharmacotherapy. Natural language processing (NLP) is a useful approach for analyzing unstructured text data, such as patient narratives. However, few...
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