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Database Management Systems

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Evaluating a Hierarchical Clinical Event Linkage Model for Clinic-Specific Databases.

Studies in health technology and informatics
A relational database model is presented that stores the hierarchical linkages between clinical events with qualifier codes, such that the explicit contextual meaning of an event's attributes is preserved upon retrieval. A retrospective analysis of 3...

Constructing a Graph Database for Semantic Literature-Based Discovery.

Studies in health technology and informatics
Literature-based discovery (LBD) generates discoveries, or hypotheses, by combining what is already known in the literature. Potential discoveries have the form of relations between biomedical concepts; for example, a drug may be determined to treat ...

Consumer Health Vocabulary: A Proposal for a Brazilian Portuguese Language.

Studies in health technology and informatics
Studies show a gap between the expressions commonly used by health consumers and health professionals. To bridge this gap, consumer health vocabularies are presented as a solution. The aim of this paper is to describe an on-going project to create a ...

Cohort Discovery Query Optimization via Computable Controlled Vocabulary Versioning.

Studies in health technology and informatics
Self-service cohort discovery tools strive to provide intuitive interfaces to large Clinical Data Warehouses that contain extensive historic information. In those tools, controlled vocabulary (e.g., ICD-9-CM, CPT) coded clinical information is often ...

Development of Markup Language for Medical Record Charting: A Charting Language.

Studies in health technology and informatics
Nowadays a lot of trials for collecting electronic medical records (EMRs) exist. However, structuring data format for EMR is an especially labour-intensive task for practitioners. Here we propose a new mark-up language for medical record charting (ca...

An efficient algorithm for updating regular expression indexes in RDF databases.

International journal of data mining and bioinformatics
The Resource Description Framework (RDF) is widely used for sharing biomedical data, such as gene ontology or the online protein database UniProt. SPARQL is a native query language for RDF, featuring regular expressions in queries for which exact val...

Managing changes in distributed biomedical ontologies using hierarchical distributed graph transformation.

International journal of data mining and bioinformatics
The issue of ontology evolution and change management is inadequately addressed by available tools and algorithms, mostly due to the lack of suitable knowledge representation formalisms to deal with temporal abstract notations and the overreliance on...

A concept ideation framework for medical device design.

Journal of biomedical informatics
Medical device design is a challenging process, often requiring collaboration between medical and engineering domain experts. This collaboration can be best institutionalized through systematic knowledge transfer between the two domains coupled with ...

ProCon - PROteomics CONversion tool.

Journal of proteomics
With the growing amount of experimental data produced in proteomics experiments and the requirements/recommendations of journals in the proteomics field to publicly make available data described in papers, a need for long-term storage of proteomics d...

Genome Modeling System: A Knowledge Management Platform for Genomics.

PLoS computational biology
In this work, we present the Genome Modeling System (GMS), an analysis information management system capable of executing automated genome analysis pipelines at a massive scale. The GMS framework provides detailed tracking of samples and data coupled...