AIMC Topic: Flow Cytometry

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Convolutional Neural Network-Driven Impedance Flow Cytometry for Accurate Bacterial Differentiation.

Analytical chemistry
Impedance flow cytometry (IFC) has been demonstrated to be an efficient tool for label-free bacterial investigation to obtain the electrical properties in real time. However, the accurate differentiation of different species of bacteria by IFC techno...

Perspectives on label-free microscopy of heterogeneous and dynamic biological systems.

Journal of biomedical optics
SIGNIFICANCE: Advancements in label-free microscopy could provide real-time, non-invasive imaging with unique sources of contrast and automated standardized analysis to characterize heterogeneous and dynamic biological processes. These tools would ov...

MAGIC-DR: An interpretable machine-learning guided approach for acute myeloid leukemia measurable residual disease analysis.

Cytometry. Part B, Clinical cytometry
Multiparameter flow cytometry is widely used for acute myeloid leukemia minimal residual disease testing (AML MRD) but is time consuming and demands substantial expertise. Machine learning offers potential advancements in accuracy and efficiency, but...

Recommendations for using artificial intelligence in clinical flow cytometry.

Cytometry. Part B, Clinical cytometry
Flow cytometry is a key clinical tool in the diagnosis of many hematologic malignancies and traditionally requires close inspection of digital data by hematopathologists with expert domain knowledge. Advances in artificial intelligence (AI) are trans...

Translating the regulatory landscape of medical devices to create fit-for-purpose artificial intelligence (AI) cytometry solutions.

Cytometry. Part B, Clinical cytometry
The implementation of medical software and artificial intelligence (AI) algorithms into routine clinical cytometry diagnostic practice requires a thorough understanding of regulatory requirements and challenges throughout the cytometry software produ...

Convolutional neuronal network for identifying single-cell-platelet-platelet-aggregates in human whole blood using imaging flow cytometry.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
Imaging flow cytometry is an attractive method to investigate individual cells by optical properties. However, imaging flow cytometry applications with clinical relevance are scarce so far. Platelet aggregation naturally occurs during blood coagulati...

Leukocyte differential based on an imaging and impedance flow cytometry of microfluidics coupled with deep neural networks.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
The differential of leukocytes functions as the first indicator in clinical examinations. However, microscopic examinations suffered from key limitations of low throughputs in classifying leukocytes while commercially available hematology analyzers f...

What are the most relevant publications in Clinical Microbiology in the last two years?

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia
This minireview describes some of the articles published in the last two years related to innovative technologies including CRISPR-Cas, surface-enhanced Raman spectroscopy, microfluidics, flow cytometry, Fourier transform infrared spectroscopy, and a...

Interpretable unsupervised learning enables accurate clustering with high-throughput imaging flow cytometry.

Scientific reports
A primary challenge of high-throughput imaging flow cytometry (IFC) is to analyze the vast amount of imaging data, especially in applications where ground truth labels are unavailable or hard to obtain. We present an unsupervised deep embedding algor...

Label-Free CD34+ Cell Identification Using Deep Learning and Lens-Free Shadow Imaging Technology.

Biosensors
Accurate and efficient classification and quantification of CD34+ cells are essential for the diagnosis and monitoring of leukemia. Current methods, such as flow cytometry, are complex, time-consuming, and require specialized expertise and equipment....