AIMC Topic: Flow Cytometry

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flowSim: Near duplicate detection for flow cytometry data.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
The analysis of large amounts of data is important for the development of machine learning (ML) models. flowSim is the first algorithm designed to visualize, detect and remove highly redundant information in flow cytometry (FCM) training sets to decr...

Real-time fluorescence imaging flow cytometry enabled by motion deblurring and deep learning algorithms.

Lab on a chip
Fluorescence imaging flow cytometry (IFC) has been demonstrated as a crucial biomedical technique for analyzing specific cell subpopulations from heterogeneous cellular populations. However, the high-speed flow of fluorescent cells leads to motion bl...

Acute psychological stress-induced progenitor cell mobilization and cardiovascular events.

Journal of psychosomatic research
OBJECTIVE: Certain brain activation responses to psychological stress are associated with worse outcomes in CVD patients. We hypothesized that elevated acute psychological stress, manifesting as greater activity within neural centers for emotional re...

Artificial Intelligence for Clinical Flow Cytometry.

Clinics in laboratory medicine
In this review, the authors discuss the fundamental principles of machine learning. They explore recent studies and approaches in implementing machine learning into flow cytometry workflows. These applications are promising but not without their shor...

A review on intelligent impedance cytometry systems: Development, applications and advances.

Analytica chimica acta
Impedance cytometry is a well-established technique for counting and analyzing single cells, with several advantages, such as convenience, high throughput, and no labeling required. A typical experiment consists of the following steps: single-cell me...

Optical time-stretch imaging flow cytometry in the compressed domain.

Journal of biophotonics
Imaging flow cytometry based on optical time-stretch (OTS) imaging combined with a microfluidic chip attracts much attention in the large-scale single-cell analysis due to its high throughput, high precision, and label-free operation. Compressive sen...

Label-free liquid biopsy through the identification of tumor cells by machine learning-powered tomographic phase imaging flow cytometry.

Scientific reports
Image-based identification of circulating tumor cells in microfluidic cytometry condition is one of the most challenging perspectives in the Liquid Biopsy scenario. Here we show a machine learning-powered tomographic phase imaging flow cytometry syst...

Cell damage evaluation by intelligent imaging flow cytometry.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
Essential thrombocythemia (ET) is an uncommon situation in which the body produces too many platelets. This can cause blood clots anywhere in the body and results in various symptoms and even strokes or heart attacks. Removing excessive platelets usi...

Artificial intelligence in clinical multiparameter flow cytometry and mass cytometry-key tools and progress.

Seminars in diagnostic pathology
There are many research studies and emerging tools using artificial intelligence (AI) and machine learning to augment flow and mass cytometry workflows. Emerging AI tools can quickly identify common cell populations with continuous improvement of acc...

Automated quantification of measurable residual disease in chronic lymphocytic leukemia using an artificial intelligence-assisted workflow.

Cytometry. Part B, Clinical cytometry
Detection of measurable residual disease (MRD) in chronic lymphocytic leukemia (CLL) is an important prognostic marker. The most common CLL MRD method in current use is multiparameter flow cytometry, but availability is limited by the need for expert...