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Stem Cells

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Effects of aqueous and ethanolic extracts of Chinese propolis on dental pulp stem cell viability, migration and cytokine expression.

PeerJ
BACKGROUND: Propolis is a natural substance produced by honeybees that has various biological properties including, anti-inflammatory, antioxidant and antimicrobial properties. Although previous studies have evaluated the antimicrobial effects of pro...

Effect of Boswellic Acid on Viability of Dental Pulp Stem Cells Compared to the Commonly Used Intracanal Medications: An Study.

The journal of contemporary dental practice
AIM: This study was aimed at evaluating the effect of acetyl-11-keto-β-boswellic acid (AKBA) on dental pulp stem cells (DPSCs) viability and proliferation to be used as a potential root canal medicament.

Acute psychological stress-induced progenitor cell mobilization and cardiovascular events.

Journal of psychosomatic research
OBJECTIVE: Certain brain activation responses to psychological stress are associated with worse outcomes in CVD patients. We hypothesized that elevated acute psychological stress, manifesting as greater activity within neural centers for emotional re...

Robot-assisted in situ bioprinting of gelatin methacrylate hydrogels with stem cells induces hair follicle-inclusive skin regeneration.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Large skin defects caused by accidents or disease can cause fluid loss, water and electrolyte disorders, hypoproteinemia and serious infection and remain a difficult problem in clinical practice. In situ bioprinting is a promising, recently developed...

Predicting multipotency of human adult stem cells derived from various donors through deep learning.

Scientific reports
Adult stem cell-based therapeutic approaches have great potential in regenerative medicine because of their immunoregulatory properties and multidifferentiation capacity. Nevertheless, the outcomes of stem cell‑based therapies to date have shown inco...

Detection of spermatogonial stem/progenitor cells in prepubertal mouse testis with deep learning.

Journal of assisted reproduction and genetics
PURPOSE: Rapid and easy detection of spermatogonial stem/progenitor cells (SSPCs) is crucial for clinicians dealing with male infertility caused by prepubertal testicular damage. Deep learning (DL) methods may offer visual tools for tracking SSPCs on...

How Brain Organoids Are Revolutionizing Neuroscience.

IEEE pulse
Measuring just a millimeter or two in diameter, brain organoids are a far cry from a fully functioning human brain. But these miniature tissues, typically derived from stem cells, are increasingly able to mimic the structure and function of our most ...

Triplet-Net Classification of Contiguous Stem Cell Microscopy Images.

IEEE/ACM transactions on computational biology and bioinformatics
Cellular microscopy imaging is a common form of data acquisition for biological experimentation. Observation of gray-level morphological features allows for the inference of useful biological information such as cellular health and growth status. Cel...

The global evolution and impact of systems biology and artificial intelligence in stem cell research and therapeutics development: a scoping review.

Stem cells (Dayton, Ohio)
Advanced bioinformatics analysis, such as systems biology (SysBio) and artificial intelligence (AI) approaches, including machine learning (ML) and deep learning (DL), is increasingly present in stem cell (SC) research. An approximate timeline on the...

Toward Machine Learning Electrospray Ionization Sensitivity Prediction for Semiquantitative Lipidomics in Stem Cells.

Journal of chemical information and modeling
Specificity, sensitivity, and high metabolite coverage make mass spectrometry (MS) one of the most valuable tools in metabolomics and lipidomics. However, translation of metabolomics MS methods to multiyear studies conducted across multiple batches i...